Purified anti-human FcμR (FAIM3) Antibody
- 产品名称：
- Purified anti-human FcμR (FAIM3) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 398102
- 产品应用：
- 398102
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- BW5147 cells expressing human FCMR protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Application Notes
It was reported that HM7 antibody can block binding of human IgM to FCMR.
- Application References
(PubMed link indicates BioLegend citation) -
- Kubagawa H, et al. 2009. J Exp Med. 206(12): 2779-93.
- Kubagawa H, et al. 2014. Monoclon Antib Immunodiagn Immunother. 33(6): 393– 400.
- RRID
- AB_2814380 (BioLegend Cat. No. 398102)
- Structure
- ~60 kD transmembranesialoglycoprotein extracellular Ig-like domain
- Distribution
-
B and T lymphocytes, natural killer (NK) cells, chronic lymphocytic leukemia cells, some lymphoid leukemia or lymphoma cell lines
- Function
- Regulates both the cell surface expression and the function of BCR, regulates humoral immune responses
- Ligand/Receptor
- IgM Fc
- Cell Type
- B cells
- Biology Area
- Adaptive Immunity, Immunology, Signal Transduction
- Molecular Family
- Fc Receptors
- Antigen References
-
- Kubagawa H, et al. 2009. J Exp Med. 206(12): 2779-93.
- Shima H, et al. 2010. Int Immunol. 22(3): 149-56.
- Kubagawa H, et al. 2019. Front Immunol. 10:945.
- Meryk A, et al. 2019. Cell Rep. 26(10): 2681-91.
- Liu J, et al. 2019. Front Immunol. 10:529.
- Gene ID
- 9214 View all products for this Gene ID
- UniProt
- View information about Fc muR on UniProt.org
