PE/Cyanine7 anti-human FcμR (FAIM3) Antibody
- 产品名称：
- PE/Cyanine7 anti-human FcμR (FAIM3) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 398105
- 产品应用：
- 398105
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1908 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- BW5147 cells expressing human FCMR protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?L per million cells in 100 ?L staining volume or 5 ?L per 100 ?L of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
It was reported that HM7 antibody can block binding of human IgM to FCMR.
- Application References
(PubMed link indicates BioLegend citation) -
- Kubagawa H, et al. 2009. J Exp Med. 206(12): 2779-93.
- Kubagawa H, et al. 2014. Monoclon Antib Immunodiagn Immunother. 33(6): 393– 400.
- RRID
- AB_2860992 (BioLegend Cat. No. 398105) AB_2860993 (BioLegend Cat. No. 398106)
- Structure
- ~60 kD transmembranesialoglycoprotein extracellular Ig-like domain
- Distribution
-
B and T lymphocytes, natural killer (NK) cells, chronic lymphocytic leukemia cells, some lymphoid leukemia or lymphoma cell lines
- Function
- Regulates both the cell surface expression and the function of BCR, regulates humoral immune responses
- Ligand/Receptor
- IgM Fc
- Cell Type
- B cells
- Biology Area
- Adaptive Immunity, Immunology, Signal Transduction
- Molecular Family
- Fc Receptors
- Antigen References
-
- Kubagawa H, et al. 2009. J Exp Med. 206(12): 2779-93.
- Shima H, et al. 2010. Int Immunol. 22(3): 149-56.
- Kubagawa H, et al. 2019. Front Immunol. 10:945.
- Meryk A, et al. 2019. Cell Rep. 26(10): 2681-91.
- Liu J, et al. 2019. Front Immunol. 10:529.
- Gene ID
- 9214 View all products for this Gene ID
- UniProt
- View information about Fc muR on UniProt.org
