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Purified anti-mouse CD34 Antibody
产品名称:
Purified anti-mouse CD34 Antibody
产品类别:
抗体
产品编号:
128601
产品应用:
128601
[价格]
规格 价格 库存
50µg ¥ 852 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Armenian Hamster
Immunogen
Mouse CD34 transfected BHK cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

The HM34 antibody does not stain bone marrow cells like some other mouse CD34 antibodies, probably because the antibody recognizes a different epitope from other mAbs.

Product Citations
  1. Sereni L, et al. 2018. J Allergy Clin Immunol. 142:1272. PubMed
  2. Iida Y, et al. 2020. J Immunother Cancer. 8:. PubMed
RRID
AB_1236364 (BioLegend Cat. No. 128601)

Antigen Details

Structure
Type I membrane protein, highly glycosylated, 75-120 kd, two isoforms reported.
Distribution

Hematopoietic progenitors, brain, testis, endothelial cells

Function
Possible adhesion molecules thought to function in early hematopoiesis by mediating attachment of stem cells to bone marrow extracellular matrix or stromal cells. Present carbohydrate ligands to selectins.
Ligand/Receptor
L-selectin, and others.
Cell Type
Endothelial cells, Hematopoietic stem and progenitors
Biology Area
Cell Biology, Immunology, Neuroinflammation, Neuroscience
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Garlanda C, et al. 1997. Eur J Cell Biol 73:368
2. Brown J, et al. 1991. Int Immunol 3:175

Gene ID
12490 View all products for this Gene ID
UniProt
View information about CD34 on UniProt.org

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