PE anti-mouse CD34 Antibody
- 产品名称：
- PE anti-mouse CD34 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 128609
- 产品应用：
- 128609
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Armenian Hamster
- Immunogen
- Mouse CD34 transfected BHK cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
The HM34 antibody does not stain bone marrow cells like some other mouse CD34 antibodies, probably because the antibody recognizes a different epitope from other mAbs.
- Product Citations
-
- Jabbar S, et al. 2022. Exp Hematol Oncol. 11:83. PubMed
- Labuhn M, et al. 2020. Cancer Cell. 36(2):123-138. PubMed
- Fan C, et al. 2020. Stem Cell Res Ther. 0.765277778. PubMed
- Zhang W, et al. 2021. Cell Prolif. 54:e13058. PubMed
- Barman PK, et al. 2019. J Immunol. 202:2720. PubMed
- Hu Q, et al. 2018. Nat Biomed Eng. 0.660416667. PubMed
- Shen YC, et al. 2021. Nat Commun. 12:3876. PubMed
- Elahi S, et al. 2020. Stem Cell Res. 43:101710. PubMed
- Uderhardt S, et al. 2019. Cell. 177:541. PubMed
- Ayari A, et al. 2020. Commun Biol. 3:237. PubMed
- Hertzano R, et al. 2020. Laryngoscope. . PubMed
- Schuettpelz L, et al. 2012. Blood. 120:2981. PubMed
- Woods B, et al. 2019. Clin Cancer Res. 25:5901. PubMed
- Huang X, et al. 2020. Mol Med Rep. 1.728472222. PubMed
- Nasti A, et al. 2017. Eur J Immunol. 47:2163. PubMed
- RRID
- AB_2074602 (BioLegend Cat. No. 128609) AB_2074601 (BioLegend Cat. No. 128610)
- Structure
- Type I membrane protein, highly glycosylated, 75-120 kd, two isoforms reported.
- Distribution
-
Hematopoietic progenitors, brain, testis, endothelial cells
- Function
- Possible adhesion molecules thought to function in early hematopoiesis by mediating attachment of stem cells to bone marrow extracellular matrix or stromal cells. Present carbohydrate ligands to selectins.
- Ligand/Receptor
- L-selectin, and others.
- Cell Type
- Endothelial cells, Hematopoietic stem and progenitors
- Biology Area
- Cell Biology, Immunology, Neuroinflammation, Neuroscience
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Garlanda C, et al. 1997. Eur J Cell Biol 73:368
2. Brown J, et al. 1991. Int Immunol 3:175
- Gene ID
- 12490 View all products for this Gene ID
- UniProt
- View information about CD34 on UniProt.org
