APC anti-mouse CD34 Antibody
- 产品名称：
- APC anti-mouse CD34 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 128611
- 产品应用：
- 128611
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Armenian Hamster
- Immunogen
- Mouse CD34 transfected BHK cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Red Laser (633 nm)
- Application Notes
The HM34 antibody does not stain bone marrow cells like some other mouse CD34 antibodies, probably because the antibody recognizes a different epitope from other mAbs.
- Product Citations
-
- Chung Y, et al. 2014. J Vis Exp. 89: 51660. PubMed
- Domingues AF, et al. 2020. Elife. 9:e51754. PubMed
- Dusseault J, et al. 2016. Diabetes. 65: 2652 - 2666. PubMed
- Yin M et al. 2019. Cell Rep. 27(9):2709-2724 . PubMed
- Helm M, et al. 2022. Life (Basel). 12:. PubMed
- Huang Z, et al. 2020. Mol Med Rep. 1.979166667. PubMed
- Park M, et al. 2021. BMB Rep. 54:470. PubMed
- Shimokawa C et al. 2017. Immunity. 46(5):863-874 . PubMed
- Hou M, et al. 2020. Stem Cell Res Ther. 11:55. PubMed
- Ye P, et al. 2022. Front Cardiovasc Med. 8:810477. PubMed
- Elahi S, et al. 2020. Stem Cell Res. 43:101710. PubMed
- Hepler C et al. 2018. eLife. 7 pii: e39636. PubMed
- Wara AK, et al. 2020. Cell Rep. 33:108550. PubMed
- Fang H, et al. 2020. Nat Commun. 4.661805556. PubMed
- Duarte D, et al. 2018. Cell Stem Cell. 22:64. PubMed
- Eislmayr K, et al. 2022. Sci Adv. 8:eabj7293. PubMed
- Singhal P, et al. 2016. Proc Natl Acad Sci U S A. 113: 122 - 127. PubMed
- Siolas D, et al. 2021. Cell Reports. 36(8):109578. PubMed
- Aryal B, et al. 2016. Nat Commun. 7:12313. PubMed
- Ngkelo A, et al. 2016. J Exp Med. 213: 1353 - 1374. PubMed
- Cruz F, et al. 2016. Stem Cells Trans Med. 5: 488-499. PubMed
- RRID
- AB_10553895 (BioLegend Cat. No. 128611) AB_10553896 (BioLegend Cat. No. 128612)
- Structure
- Type I membrane protein, highly glycosylated, 75-120 kd, two isoforms reported.
- Distribution
-
Hematopoietic progenitors, brain, testis, endothelial cells
- Function
- Possible adhesion molecules thought to function in early hematopoiesis by mediating attachment of stem cells to bone marrow extracellular matrix or stromal cells. Present carbohydrate ligands to selectins.
- Ligand/Receptor
- L-selectin, and others.
- Cell Type
- Endothelial cells, Hematopoietic stem and progenitors
- Biology Area
- Cell Biology, Immunology, Neuroinflammation, Neuroscience
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Garlanda C, et al. 1997. Eur J Cell Biol 73:368
2. Brown J, et al. 1991. Int Immunol 3:175
- Gene ID
- 12490 View all products for this Gene ID
- UniProt
- View information about CD34 on UniProt.org
