热线电话: 021-34661275
产品分类/PRODUCT CLASSIFICATION

上海细胞库

人源细胞系| 稳转细胞系| 基因敲除株| 基因点突变细胞株| 基因过表达细胞株| 重组细胞系| 猪的细胞系| 马细胞系| 兔的细胞系| 犬的细胞系| 山羊的细胞系| 鱼的细胞系| 猴的细胞系| 仓鼠的细胞系| 狗的细胞系| 牛的细胞| 大鼠细胞系| 小鼠细胞系| 其他细胞系|

原代细胞

原代细胞| 永生化细胞|

细胞培养

血清| 无血清冻存| 细胞培养试剂盒| 普通培养基| 完全培养基| 细胞污染预防| 细胞污染清除| 细胞培养辅助试剂|

细胞服务

STR鉴定服务| ATCC代购服务|

酶联试剂盒

人ELISA试剂盒| 大鼠ELISA试剂盒| 小鼠ELISA试剂盒| 兔ELISA试剂盒| 猪ELISA试剂盒| 鱼ELISA试剂盒| 牛ELISA试剂盒| 犬ELISA试剂盒| 鸭ELISA试剂盒| 豚鼠ELISA试剂盒| 鸡ELISA试剂盒| 绵羊ELISA试剂盒| 山羊ELISA试剂盒| 仓鼠ELISA试剂盒| 植物ELISA试剂盒| 药残留类试剂盒| 其他ELISA试剂盒|

生化试剂盒

生化试剂盒| 微量法检测盒| 分光法检测盒| 胶体金检测盒|

PCR试剂盒

荧光探针PCR试剂盒| 染料荧光PCR试剂盒| 核酸扩增/纯化| 普通PCR检测试剂盒| 质粒菌种感受态|

抗体蛋白

蛋白多肽| 抗体| 免疫组化| 免疫球蛋白|

试剂耗材

标准试液| 科研试剂| 缓 冲 液| 实验耗材| 高效液相色谱对照品|

首页 > 抗体蛋白 > 抗体
APC/Cyanine7 anti-mouse Ly-6C Antibody
产品名称：
APC/Cyanine7 anti-mouse Ly-6C Antibody
产品类别：
抗体
产品编号：
128025
产品应用：
128025
[价格]
规格 价格 库存
25µg ￥ 1548 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
L3 cloned CTL cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography and conjugated with APC/Cyanine7 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is =0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application Notes

Clone HK1.4 does not block the binding of clone RB6-8C58.

Additional reported applications (for relevant formats of this clone) include: in vitro activation of T cells1-3 and immunohistochemistry of frozen sections4.

Additional Product Notes
BioLegend is in the process of converting the name APC/Cy7 to APC/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our APC/Cyanine7 products. Please contact Technical Service if you have any questions.
Application References

(PubMed link indicates BioLegend citation)
  1. Jutila MA, et al. 1988. Eur. J. Immunol. 18:1819. (Activ)
  2. Herold KC, et al. 1990. Diabetes 39:815. (Activ)
  3. Havran WL, et al. 1988. J. Immunol. 140:1034 (Activ)
  4. Flanagan K, et al. 2008. J. Immunol. 180:3874. (IHC)
  5. Makaroff LE, et al. 2009. P. Natl. Acad. Sci. USA 106:4799. (FC)
  6. Zuber J, et al. 2009. Genes Dev. 23:877. (FC) PubMed
  7. Ribechini E, et al. 2009. Eur. J. Immunol. 39:3538.
  8. Ma C, et al. 2012. J. Leukoc. Biol. 92:1199.
  9. Watson NB, et al. 2015. J Immunol. 194:2796. PubMed
Product Citations
  1. Parsons M, et al. 2014. J Immunol. 192:1361. PubMed
  2. Sun L, et al. 2021. Cancer Cell. :. PubMed
  3. He J, et al. 2022. Front Immunol. 12:760138. PubMed
  4. Ippagunta S, et al. 2016. Proc Natl Acad Sci U S A. 113: E6162 - E6171. PubMed
  5. Rodriguez-García A, et al. 2021. Nat Commun. 12:877. PubMed
  6. Súarez-López L, et al. 2021. iScience. 24:103406. PubMed
  7. Sun CP, et al. 2021. PLoS Pathog. 17:e1009758. PubMed
  8. Abdala-Valencia H, et al. 2014. Am J Physiol Lung Cell Mol Physiol. 307:482. PubMed
  9. Kim AS, et al. 2021. Cell. 184(17):4414-4429.e19. PubMed
  10. Heng Y, et al. 2020. Glia. . PubMed
  11. Chou YJ, et al. 2020. Sci Rep. 10:8422. PubMed
  12. Devalaraja S, et al. 2020. Cell. 1098:180. PubMed
  13. de Mingo Pulido , et al. 2021. Immunity. 54(6):1154-1167.e7. PubMed
  14. ?lvaro de Mingo Pulido et al. 2018. Cancer cell. 33(1):60-74 . PubMed
  15. Tanner MA, et al. 2021. Am J Physiol Heart Circ Physiol. 321:H633. PubMed
  16. McDowell SAC, et al. 2021. Nat Cancer. 2:545. PubMed
  17. Zhou HF, et al. 2022. Front Pharmacol. 13:778755. PubMed
  18. Royzman D, et al. 2022. Front Immunol. 13:1012647. PubMed
  19. Lin T, et al. 2015. PLoS One. 10: e0138335. PubMed
  20. Wada N, et al. 2020. Mol Metab. 37:100988. PubMed
  21. Motoyama S, et al. 2020. Cells. :9. PubMed
  22. Chan YH, et al. 2019. EMBO Mol Med. 11:e10092. PubMed
  23. Walker FC, et al. 2021. PLoS Pathog. 17:e1009402. PubMed
  24. Movita D, et al. 2015. J Virol. 89:4809. PubMed
  25. Devalaraja S, et al. 2020. STAR Protoc. 1:100188. PubMed
  26. Hou X, et al. 2022. Cell Death Dis. 13:100. PubMed
  27. Fujita K, et al. 2019. Proc Natl Acad Sci U S A. 116:14714. PubMed
  28. Yu S, et al. 2016. Mol Ther. 10.1038/mt.2016.175. PubMed
  29. Yin S, et al. 2016. Nat Commun. 7: 11311. PubMed
  30. Domingos-Pereira S, et al. 2019. Cancer Immunol Res. 7:621. PubMed
  31. Wang Y, et al. 2021. Cell Rep. 35:108948. PubMed
  32. Formaglio P, et al. 2021. Immunity. 54:2724. PubMed
  33. Neupane AS, et al. 2020. Cell. 183(1):110-125.e11. PubMed
  34. Abdul Pari AA, et al. 2020. Cancer Res. 80:2586. PubMed
  35. Lim HY et al. 2018. Immunity. 49(2):326-341 . PubMed
  36. Guérin MV, et al. 2019. Nat Commun. 10:4131. PubMed
  37. Witkowski MT, et al. 2020. Cancer Cell. 37:867. PubMed
  38. McFarland AP, et al. 2021. Immunity. 54(6):1320-1337.e4. PubMed
  39. Bambouskova M, et al. 2021. Cell Reports. 34(10):108756. PubMed
  40. AM C, et al. 2015. Proc Natl Acad Sci U S A. 112 7557 . PubMed
  41. Dmitrieva‐Posocco O et al. 2019. Immunity. 50(1):166-180 . PubMed
  42. Kuhn JA, et al. 2021. Elife. 10:. PubMed
  43. Lin J, et al. 2021. Nat Commun. 12:5321. PubMed
  44. Terauchi R, et al. 2021. PLoS One. 16:e0239108. PubMed
  45. Wang SK, et al. 2021. JCI Insight. 6: . PubMed
  46. Liu X, et al. 2020. Cell Host Microbe. 28(5):683-698.e6. PubMed
  47. Grauel AL, et al. 2020. Nat Commun. 4.84375. PubMed
  48. Lee L, et al. 2016. PLoS One. 11:e0167693. PubMed
  49. Maisel D, et al. 2016. PLoS One. 11: 0159716. PubMed
  50. Sim?es FC, et al. 2020. Nat Commun. 0.875. PubMed
  51. Luo J et al. 2018. Immunity. 49(1):107-119 . PubMed
  52. Shepardson K, et al. 2016. MBio. 7: e00506-16. PubMed
  53. Alam Z, et al. 2020. Cell Rep. 107825:31. PubMed
  54. Mossadegh–Keller N, et al. 2019. Bio Protoc. 9:5. PubMed
  55. Mohamed E, et al. 2020. Immunity. 52(4):668-682.e7.. PubMed
  56. Olson B, et al. 2021. Brain Behav Immun. 97:102. PubMed
  57. Swanson P, et al. 2016. PLoS Pathog. 12:e1006022. PubMed
  58. Capuccini B, et al. 2016. Sci Rep. 6:39258. PubMed
  59. de Laval B, et al. 2020. Cell Stem Cell. 26(5):657-674. PubMed
  60. Walker MT, et al. 2021. Front. Allergy. 2:. PubMed
  61. Mulens-Arias V, et al. 2022. Pharmaceutics. 14:. PubMed
  62. Bellomo A, et al. 2020. Immunity. 53(1):127-142.e7. PubMed
  63. Evrard M et al. 2018. Immunity. 48(2):364-379 . PubMed
  64. Alexander Mildner et al. 2017. Immunity. 46(5):849-862 . PubMed
  65. Buerfent BC, et al. 2019. GMS Infect Dis. 7:Doc04. PubMed
  66. Clemente–Casares X, et al. 2017. Immunity. 47:974. PubMed
  67. Fedele C, et al. 2021. J Exp Med. 218: . PubMed
  68. Nicolas-Boluda A, et al. 2021. eLife. 10:00. PubMed
  69. Kwok I, et al. 2020. Immunity. 53(2):303-318.e5. PubMed
  70. van de Garde M, et al. 2016. PLoS One. 11:e0166094. PubMed
  71. Baker GJ, et al. 2020. Cell Syst. 0.647222222. PubMed
  72. Gardner A, et al. 2022. J Immunother Cancer. 10:. PubMed
  73. Heyde A, et al. 2021. Cell. 184(5):1348-1361.e22. PubMed
  74. Zhang X, et al. 2020. Glia. . PubMed
  75. Lynn GM, et al. 2020. Nat Biotechnol. 38:320. PubMed
RRID
AB_10643867 (BioLegend Cat. No. 128025) AB_10640120 (BioLegend Cat. No. 128026)

Antigen Details

Structure
14-17 kD protein (134 amino acids), member of the Ly-6 family of GPI linked protein. Ly6 family members share structure homology throughout a distinctive cystein rich protein domain that incorporates O-linked carbohydrates.
Distribution

Ly-6C is expressed primarily on bone marrow myeloid populations, monocytes/macrophages, neutrophils, endothelial cells, and some T cell subsets. Ly-6C is also a marker of memory CD8+ T cells.

Cell Type
Endothelial cells, Macrophages, Monocytes, Neutrophils, T cells
Biology Area
Immunology
Molecular Family
CD Molecules
Antigen References

1. Jutila MA, et al. 1988. Eur. J. Immunol. 18:1819.
2. Cerwenka A, et al. 1998. J. Immunol. 161:97.

Gene ID
17067 View all products for this Gene ID
UniProt
View information about Ly-6C on UniProt.org

联系我们

TEL：021-34661275 　点击拨打热线