PE anti-human CD38 Antibody
- 产品名称：
- PE anti-human CD38 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 303505
- 产品应用：
- 303505
- Verified Reactivity
- Human
- Reported Reactivity
- Chimpanzee, Horse, Cow
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections6?and spatial biology (IBEX)10,11.
- Application References
(PubMed link indicates BioLegend citation) -
- Kishimoto T, et al. Eds. 1997. Leucocyte Typing VI. Garland Publishing Inc. London.
- Dieu M. 1998. J. Exp. Med. 188:373.
- Esser M, et al. 2001. J. Virol. 75:6173.
- Jeannin P, et al. 1999. J. Immunol. 162:2044.
- Kapsogeorgou EK, et al. 2001. J. Immunol. 166:3107.
- van der Voort R, et al. 1997. J. Exp. Med. 185:2121. (IHC)
- Bende RJ, et al. 2003. Am. J. Pathol. 162:105.
- Lehner M, et al. 2008. J. Leukoc. Biol. 83:883. PubMed
- Yoshino N, et al. 2000. Exp. Anim. (Tokyo) 49:97. (FC)
- Radtke AJ,?et al. 2020.?Proc Natl Acad Sci USA. 117:33455-33465. (SB)?PubMed
- Radtke AJ,?et al. 2022.?Nat Protoc. 17:378-401. (SB)?PubMed
- Product Citations
-
- Schelker RC, et al. 2018. Hematology. 1.192361111. PubMed
- Rosendahl Huber A, et al. 2022. STAR Protoc. 3:101361. PubMed
- Brandsma AM, et al. 2021. Blood Cancer Discov. 2:484. PubMed
- Yamauchi T et al. 2018. Cancer cell. 33(3):386-400 . PubMed
- Hagan T, et al. 2020. Cell. 178(6):1313-1328.e13.. PubMed
- de Kanter JK, et al. 2021. Cell Stem Cell. 28:1726. PubMed
- Hasaart KAL, et al. 2020. Sci Rep. 10:12991. PubMed
- Munteanu AN, et al. 2019. Exp Ther Med. 18:1693. PubMed
- Brandsma AM, et al. 2021. Cancer Discov. . PubMed
- Zhou L, et al. 2021. Transl Cancer Res. 10:5307. PubMed
- Kreye J, et al. 2020. Cell. 183(4):1058-1069.e19. PubMed
- Osorio FG et al. 2018. Cell reports. 25(9):2308-2316 . PubMed
- Kreye J, et al. 2020. bioRxiv. . PubMed
- Zhou L, et al. 2021. Transl Cancer Res. 10:3364. PubMed
- Fathy El-Metwaly N, et al. 2021. Asian Pac J Cancer Prev. 22:3237. PubMed
- Li Z, et al. 2014. PLoS One. 9:106064. PubMed
- Saygin C, et al. 2021. Leukemia. 35:3406. PubMed
- Hasaart KAL, et al. 2022. iScience. 25:103736. PubMed
- Csomós K, et al. 2022. Nat Immunol. 23:1256. PubMed
- RRID
- AB_314357 (BioLegend Cat. No. 303505) AB_314358 (BioLegend Cat. No. 303506)
- Structure
- ADP-ribosyl cyclase, ectoenzyme, type II glycoprotein, 45 kD
- Distribution
-
T cells, B cells, NK, myeloid, plasma, and dendritic cells
- Function
- Ecto-ADP-ribosyl cyclase, calcium signaling, cell activation
- Ligand/Receptor
- CD31, hyaluronic acid
- Cell Type
- B cells, Dendritic cells, NK cells, Plasma cells, T cells
- Biology Area
- Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Ferrero E, et al. 1999. J. Leukoc. Biol. 65:151.
2. Lund F, et al. 1995. Immunol. Today 16:469.
- Gene ID
- 952 View all products for this Gene ID
- UniProt
- View information about CD38 on UniProt.org
