APC anti-human CD38 Antibody
- 产品名称：
- APC anti-human CD38 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 303509
- 产品应用：
- 303509
- Verified Reactivity
- Human
- Reported Reactivity
- Chimpanzee, Horse, Cow
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Red Laser (633 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections6?and spatial biology (IBEX)10,11.
- Application References
(PubMed link indicates BioLegend citation) -
- Kishimoto T, et al. Eds. 1997. Leucocyte Typing VI. Garland Publishing Inc. London.
- Dieu M. 1998. J. Exp. Med. 188:373.
- Esser M, et al. 2001. J. Virol. 75:6173.
- Jeannin P, et al. 1999. J. Immunol. 162:2044.
- Kapsogeorgou EK, et al. 2001. J. Immunol. 166:3107.
- van der Voort R, et al. 1997. J. Exp. Med. 185:2121. (IHC)
- Bende RJ, et al. 2003. Am. J. Pathol. 162:105.
- Lehner M, et al. 2008. J. Leukoc. Biol. 83:883. PubMed
- Yoshino N, et al. 2000. Exp. Anim. (Tokyo) 49:97. (FC)
- Radtke AJ,?et al. 2020.?Proc Natl Acad Sci USA. 117:33455-33465. (SB)?PubMed
- Radtke AJ,?et al. 2022.?Nat Protoc. 17:378-401. (SB)?PubMed
- Product Citations
-
- Ye Y, et al. 2022. Nat Commun. 13:6458. PubMed
- Li Y, et al. 2016. Nat Commun. 7:10836. PubMed
- Tsuchida Y, et al. 2017. PLoS One. 10.1371/journal.pone.0169646. PubMed
- Causi E, et al. 2015. PLoS One. 10: 0136717. PubMed
- Mall EM, et al. 2021. PLoS One. 16:e0258427. PubMed
- Welsh JA, et al. 2022. Cell Rep Methods. 2:100136. PubMed
- Iannetta M, et al. 2016. PLoS One. 11: 0160277. PubMed
- González-Tajuelo R, et al. 2020. Front Immunol. 11:588212. PubMed
- Bange EM, et al. 2021. Nat Med. 27:1280. PubMed
- Buggert M, et al. 2014. J Immunol. 192:2099. PubMed
- Kuo HH, et al. 2018. Immunity. 48:1183. PubMed
- Lehner M, et al. 2008. J Leukoc Biol. 83:883. PubMed
- Dai J et al. 2018. Journal of immunology (Baltimore, Md. 200(5):1727-1736 . PubMed
- Buggert M, et al. 2020. Cell. 183(7):1946-1961.e15. PubMed
- Shalhout S, et al. 2014. Mol Cell Biol. 34:4019. PubMed
- Lima J, et al. 2016. Reprod Sci. 10.1177/1933719116653680. PubMed
- Sokal A, et al. 2021. Cell. 184(5):1201-1213.e14. PubMed
- Shehata L, et al. 2019. Cell Rep. 28:3300. PubMed
- Montel‐Hagen A et al. 2019. Cell stem cell. 24(3):376-389 . PubMed
- Duhen R, et al. 2021. Nat Commun. 12:1047. PubMed
- Shah GL, et al. 2020. J Clin Invest. 130:6656. PubMed
- Wang J, et al. 2020. Cell Stem Cell. 27(1):81-97. PubMed
- Wang B, et al. 2018. Mol Ther Nucleic Acids. 0.548611111. PubMed
- Ferreira-Gomes M, et al. 2021. Nat Commun. 12:1961. PubMed
- Lee CY, et al. 2021. Cancer Discov. Online ahead of print. PubMed
- Chen PM, et al. 2022. Sci Adv. 8:eabo4271. PubMed
- Lubaki N, et al. 2016. PLoS Pathog. 12:e1006031. PubMed
- RRID
- AB_314361 (BioLegend Cat. No. 303509) AB_314362 (BioLegend Cat. No. 303510)
- Structure
- ADP-ribosyl cyclase, ectoenzyme, type II glycoprotein, 45 kD
- Distribution
-
T cells, B cells, NK, myeloid, plasma, and dendritic cells
- Function
- Ecto-ADP-ribosyl cyclase, calcium signaling, cell activation
- Ligand/Receptor
- CD31, hyaluronic acid
- Cell Type
- B cells, Dendritic cells, NK cells, Plasma cells, T cells
- Biology Area
- Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Ferrero E, et al. 1999. J. Leukoc. Biol. 65:151.
2. Lund F, et al. 1995. Immunol. Today 16:469.
- Gene ID
- 952 View all products for this Gene ID
- UniProt
- View information about CD38 on UniProt.org
