PE anti-human CD41 Antibody
- 产品名称：
- PE anti-human CD41 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 303705
- 产品应用：
- 303705
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1176 |
1 |
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon, Capuchin Monkey, Cynomolgus, Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections and blocking of platelet aggregation2. The HIP8 antibody has been reported to block the activation of platelets by various stimuli, including collagen, and ADP.
- Application References
(PubMed link indicates BioLegend citation) -
- Knapp W, et al. 1989. Leucocyte Typing IV. Oxford University Press. New York.
- McCarty OJT, et al. 2000. Blood 96:1789.
- Yoshino N, et al. 2000. Exp. Anim. (Tokyo) 49:97. (FC)
- Zhi L et al. 2013. PLoS One. 8:e79869. (IHC)
- Product Citations
-
- Liu Y, et al. 2022. Signal Transduct Target Ther. 7:347. PubMed
- Wang H, et al. 2020. Cell Stem Cell. 28(3):535-549.e8. PubMed
- Laura C Burzynski et al. 2019. Immunity. 50(4):1033-1042 . PubMed
- Abud EM et al. 2017. Neuron. 94(2):278-293 . PubMed
- Tzoran I, et al. 2015. Exp Hematol. . PubMed
- Kim HJ, et al. 2022. Sci Rep. 12:2099. PubMed
- Shen X, et al. 2020. Molecular Cell. 80(6):1013-1024.e6. PubMed
- Welsh JA, et al. 2020. J Extracell Vesicles. 9:1713526. PubMed
- Oggero S, et al. 2021. Journal of Extracellular Vesicles. 10(6):12084. PubMed
- Looi C, et al. 2011. PLoS One. 6:e23640. PubMed
- RRID
- AB_314375 (BioLegend Cat. No. 303705) AB_314376 (BioLegend Cat. No. 303706)
- Structure
- Integrin family, α subunit of CD41/CD61 (GPIIb-IIIa) complex, 125/22 kD
- Distribution
-
Platelets, megakaryocytes
- Function
- Platelet aggregation, platelet attachment to extracellular matrix
- Ligand/Receptor
- Fibrinogen, fibronectin, von Willebrand factor, thrombin
- Cell Type
- Megakaryocytes, Platelets
- Biology Area
- Cell Adhesion, Cell Biology, Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Denzin L, et al. 1996. J. Exp. Med. 184:2153.
2. Denzin L, et al. 1995. Cell 82:155.
3. Riberdy J, et al. 1994. J. Cell Biol. 125:1225.
- Gene ID
- 3674 View all products for this Gene ID
- UniProt
- View information about CD41 on UniProt.org
