FITC anti-human CD41 Antibody
- 产品名称：
- FITC anti-human CD41 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 303703
- 产品应用：
- 303703
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1008 |
1 |
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon, Capuchin Monkey, Cynomolgus, Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections and blocking of platelet aggregation2. The HIP8 antibody has been reported to block the activation of platelets by various stimuli, including collagen, and ADP.
- Application References
(PubMed link indicates BioLegend citation) -
- Knapp W, et al. 1989. Leucocyte Typing IV. Oxford University Press. New York.
- McCarty OJT, et al. 2000. Blood 96:1789.
- Yoshino N, et al. 2000. Exp. Anim. (Tokyo) 49:97. (FC)
- Zhi L et al. 2013. PLoS One. 8:e79869. (IHC)
- Product Citations
-
- Leimkühler NB, et al. 2020. Cell Stem Cell. 28:637. PubMed
- Xu Y, et al. 2021. Stem Cell Res Ther. 12:112. PubMed
- Esteghamat F, et al. 2019. Nat Genet. 51:1233. PubMed
- Long A, et al. 2016. Toxicol Pathol. 44: 998 - 1012. PubMed
- Schmidt RA, et al. 2018. Transl Res. 195:1. PubMed
- Rolfes V, et al. 2018. Oncotarget. 9:27460. PubMed
- Di Buduo CA, et al. 2021. eLife. 10:00. PubMed
- Wang X, et al. 2018. Cell Death Dis. 9:578. PubMed
- Luni C, et al. 2011. Biotechnol Prog. 27:1154. PubMed
- Jain K, et al. 2019. EBioMedicine. 1.852777778. PubMed
- Damkham N, et al. 2022. Stem Cell Res Ther. 13:467. PubMed
- Karantanos T, et al. 2022. Sci Adv. 8:eabl8952. PubMed
- Wilkes MC, et al. 2020. Nat Commun. 2.780555556. PubMed
- Gleitz HFE, et al. 2021. STAR Protocols. 2(2):100538. PubMed
- Rai R, et al. 2020. Nat Commun. 4034:11. PubMed
- Kawamoto E, et al. 2021. Biomedicines. 9:. PubMed
- Headland S, et al. 2014. Sci Rep. 4:5237. PubMed
- Dinh HQ, et al. 2020. Immunity. 53(2):319-334.e6. PubMed
- RRID
- AB_314373 (BioLegend Cat. No. 303703) AB_314374 (BioLegend Cat. No. 303704)
- Structure
- Integrin family, α subunit of CD41/CD61 (GPIIb-IIIa) complex, 125/22 kD
- Distribution
-
Platelets, megakaryocytes
- Function
- Platelet aggregation, platelet attachment to extracellular matrix
- Ligand/Receptor
- Fibrinogen, fibronectin, von Willebrand factor, thrombin
- Cell Type
- Megakaryocytes, Platelets
- Biology Area
- Cell Adhesion, Cell Biology, Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Denzin L, et al. 1996. J. Exp. Med. 184:2153.
2. Denzin L, et al. 1995. Cell 82:155.
3. Riberdy J, et al. 1994. J. Cell Biol. 125:1225.
- Gene ID
- 3674 View all products for this Gene ID
- UniProt
- View information about CD41 on UniProt.org
