APC anti-human CD41 Antibody
- 产品名称：
- APC anti-human CD41 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 303709
- 产品应用：
- 303709
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1668 |
1 |
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon, Capuchin Monkey, Cynomolgus, Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Red Laser (633 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections and blocking of platelet aggregation2. The HIP8 antibody has been reported to block the activation of platelets by various stimuli, including collagen, and ADP.
- Application References
(PubMed link indicates BioLegend citation) -
- Knapp W, et al. 1989. Leucocyte Typing IV. Oxford University Press. New York.
- McCarty OJT, et al. 2000. Blood 96:1789.
- Yoshino N, et al. 2000. Exp. Anim. (Tokyo) 49:97. (FC)
- Zhi L et al. 2013. PLoS One. 8:e79869. (IHC)
- Product Citations
-
- Liu Y, et al. 2022. Signal Transduct Target Ther. 7:347. PubMed
- Machata S, et al. 2021. Front Immunol. 11:565869. PubMed
- Moussa M, et al. 2016. J Biomater Appl. 30: 1219 - 1229. PubMed
- Botha J, et al. 2021. Biomedicines. 9:. PubMed
- Wang B, et al. 2022. Cell Discov. 8:41. PubMed
- Pircher J, et al. 2018. Nat Commun. 32:364. PubMed
- Hug S, et al. 2021. Front Immunol. 12:642867. PubMed
- Best MG et al. 2017. Cancer cell. 32(2):238-252 . PubMed
- Sato M, et al. 2021. Spine Surg Relat Res. 5:196. PubMed
- Rodda LB, et al. 2020. Cell. 184(1):169-183.e17. PubMed
- Sung PS, et al. 2019. Nat Commun. 10:2402. PubMed
- Zhang G, et al. 2021. Front Pharmacol. 12:705325. PubMed
- Shlamkovich T, et al. 2020. BMC Biology. 16(1):92. PubMed
- Pellin D, et al. 2019. Nat Commun. 10:2395. PubMed
- Ito Y, et al. 2018. Cell. 174:636. PubMed
- Palacios-Acedo AL, et al. 2021. Front Oncol. 11:704945. PubMed
- Guo Q, et al. 2022. Blood Adv. 6:5668. PubMed
- Suzuki D, et al. 2020. Stem Cell Reports. 14:49. PubMed
- Costa B, et al. 2019. Blood Adv. 3:1092. PubMed
- RRID
- AB_2129464 (BioLegend Cat. No. 303709) AB_2249385 (BioLegend Cat. No. 303710)
- Structure
- Integrin family, α subunit of CD41/CD61 (GPIIb-IIIa) complex, 125/22 kD
- Distribution
-
Platelets, megakaryocytes
- Function
- Platelet aggregation, platelet attachment to extracellular matrix
- Ligand/Receptor
- Fibrinogen, fibronectin, von Willebrand factor, thrombin
- Cell Type
- Megakaryocytes, Platelets
- Biology Area
- Cell Adhesion, Cell Biology, Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Denzin L, et al. 1996. J. Exp. Med. 184:2153.
2. Denzin L, et al. 1995. Cell 82:155.
3. Riberdy J, et al. 1994. J. Cell Biol. 125:1225.
- Gene ID
- 3674 View all products for this Gene ID
- UniProt
- View information about CD41 on UniProt.org
