Purified anti-human CD1a Antibody
- 产品名称：
- Purified anti-human CD1a Antibody
- 产品类别：
- 抗体
- 产品编号：
- 300101
- 产品应用：
- 300101
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
IHC-F - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections.
- Application References
(PubMed link indicates BioLegend citation) -
- Schlossman S, et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York.
- Knapp W. 1989. Leucocyte Typing IV. Oxford University Press New York.
- Patton KM, et al. 2005. Infect. Immun.73:2083. PubMed
- Curti A, et al. 2010. Haematologica. 95:2022. PubMed
- Product Citations
-
- Alcántara‐Hernández M et al. 2017. Immunity. 47(6):1037-1050 . PubMed
- Ortiz AM, et al. 2018. Nat Med. 24:1313. PubMed
- Laudanski K, et al. 2018. J Transl Med. 0.765972222. PubMed
- Alcántara-Hernández M, et al. 2021. Nat Protoc. 16:4855. PubMed
- Guo T, et al. 2018. J Immunol. 200:500. PubMed
- Patton K, et al. 2005. Infect Immun. 73:2083. PubMed
- Roussel M, et al. 2021. Cell Reports Medicine. 2(6):100291. PubMed
- Tjomsland V, et al. 2011. PLoS One. 6:e23542. PubMed
- Eriksson E, et al. 2017. Clin Cancer Res. 5.018055556. PubMed
- Sander J et al. 2017. Immunity. 47(6):1051-1066 . PubMed
- Leylek R, et al. 2020. Cell Rep. 32:108180. PubMed
- RRID
- AB_314015 (BioLegend Cat. No. 300101) AB_314016 (BioLegend Cat. No. 300102)
- Structure
- Ig superfamily, MHC I-like molecule, type I transmembrane glycoprotein, 49 kD
- Distribution
-
Cortical thymocytes, Langerhans cells, dendritic cells
- Function
- Antigen presentation, lymphocyte activation, thymic T cell development
- Ligand/Receptor
- CD1-restricted TCRs
- Cell Type
- Dendritic cells, Langerhans cells, Thymocytes
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules
- Antigen References
-
- Blumberg RS, et al. 1995. Immunol. Rev. 147:5.
- Calabi F, et al. 1991. Tissue Antigens 37:1.
- Melian A, et al. 1996. Curr. Opin. Immunol. 8:82.
- Gene ID
- 909 View all products for this Gene ID
- UniProt
- View information about CD1a on UniProt.org
