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FITC anti-human CD1a Antibody
产品名称:
FITC anti-human CD1a Antibody
产品类别:
抗体
产品编号:
300103
产品应用:
300103
[价格]
规格 价格 库存
25tests ¥ 1008 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser
Blue Laser (488 nm)
Application Notes

Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections.

Application References

(PubMed link indicates BioLegend citation)
  1. Schlossman S, et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York.
  2. Knapp W. 1989. Leucocyte Typing IV. Oxford University Press New York.
  3. Patton KM, et al. 2005. Infect. Immun.73:2083. PubMed
  4. Curti A, et al. 2010. Haematologica. 95:2022. PubMed
Product Citations
  1. Mester B, et al. 2015. PLoS One. 10: e0140432. PubMed
  2. Harman A, et al. 2013. J Immunol. 190:66. PubMed
  3. Thwe PM et al. 2017. Cell metabolism. 26(3):558-567 . PubMed
  4. Palamides P, et al. 2016. Dis Model Mech. 9: 985 - 997. PubMed
  5. Curti A, et al. 2010. Haematologica. 95:2022. PubMed
  6. Bj?rklund &, et al. 2016. Nat Immunol. 17:451-460. PubMed
  7. Hansen IS, et al. 2018. Nat Commun. 9:863. PubMed
  8. Wu J, et al. 2021. Front Immunol. 12:601611. PubMed
  9. Bakdash G, et al. 2016. Cancer Res . 76: 4332 - 4346. PubMed
  10. Hurrell BP, et al. 2019. Cell Rep. 29:4509. PubMed
  11. Yang R, et al. 2020. Cell. 183(7):1826-1847.e31. PubMed
  12. Hazenberg MD, et al. 2019. Blood Adv. 2.659722222. PubMed
  13. Golebski K, et al. 2021. Immunity. 54(2):291-307.e7. PubMed
  14. Galle-Treger L, et al. 2019. Nat Commun. 10:713. PubMed
  15. Takechi H, et al. 2013. Nephrol Dial Transplant. 28:3004. PubMed
  16. Bal S, et al. 2016. Nat Immunol. 10.1038/ni.3444. PubMed
  17. Matsuyama H, et al. 2019. Sci Rep. 9:13181. PubMed
  18. Trabanelli S, et al. 2014. J Immunol. 192:1231. PubMed
  19. Bennstein SB, et al. 2020. eLife. 9:e55232.. PubMed
RRID
AB_314017 (BioLegend Cat. No. 300103) AB_314018 (BioLegend Cat. No. 300104)

Antigen Details

Structure
Ig superfamily, MHC I-like molecule, type I transmembrane glycoprotein, 49 kD
Distribution

Cortical thymocytes, Langerhans cells, dendritic cells

Function
Antigen presentation, lymphocyte activation, thymic T cell development
Ligand/Receptor
CD1-restricted TCRs
Cell Type
Dendritic cells, Langerhans cells, Thymocytes
Biology Area
Immunology, Innate Immunity
Molecular Family
CD Molecules
Antigen References
  1. Blumberg RS, et al. 1995. Immunol. Rev. 147:5.
  2. Calabi F, et al. 1991. Tissue Antigens 37:1.
  3. Melian A, et al. 1996. Curr. Opin. Immunol. 8:82.
Gene ID
909 View all products for this Gene ID
UniProt
View information about CD1a on UniProt.org

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