Purified anti-human/mouse/rat CD205 (DEC-205) Anti
- 产品名称:
- Purified anti-human/mouse/rat CD205 (DEC-205) Anti
- 产品类别:
- 抗体
- 产品编号:
- 359202
- 产品应用:
- 359202
- Verified Reactivity
- Human, Mouse, Rat
- Reported Reactivity
- Monkey
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- hDEC205-hIgG1Fc protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
IHC-F, WB - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Additional reported applications (for relevant formats) include: immunohistochemical staining of frozen tissue sections1 and Western blotting1.
- Application References
(PubMed link indicates BioLegend citation) -
- Park CG, et al. 2012. J. Immunol. Methods 377:15. (IHC, WB)
- RRID
- AB_2562362 (BioLegend Cat. No. 359202)
- Structure
- An N-terminal cysteine-rich domain, a fibronectin type II domain and a series of 10 tandemnly repeated C-type like domains (CTLDs)
- Distribution
-
Expressed at high levels by dendritic cells and thymic epithelial cells; also expressed by B lymphocytes, macrophages, Langerhans cells, bone marrow cells, and epithelial cells
- Function
- Mediates endocytosis, antigen uptake, presentation, and cross-presentation to T cells
- Cell Type
- B cells, Dendritic cells, Epithelial cells, Langerhans cells, Macrophages
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules
- Antigen References
-
1. Jiang W, et al. 1995. Nature 375:151.
2. Small M and Kraal G. 2003. Int. Immunol. 15:197.
3. Shrimpton RE, et al. 2009. Mol. Immunol. 46:1229.
- Gene ID
- 4065 View all products for this Gene ID 17076 View all products for this Gene ID 499800 View all products for this Gene ID
- UniProt
- View information about CD205 on UniProt.org