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PE anti-human/mouse/rat CD205 (DEC-205) Antibody
产品名称:
PE anti-human/mouse/rat CD205 (DEC-205) Antibody
产品类别:
抗体
产品编号:
359203
产品应用:
359203
[价格]
规格 价格 库存
25tests ¥ 1836 1

产品详情

Product Details

Verified Reactivity
Human, Mouse, Rat
Reported Reactivity
Monkey
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
hDEC205-hIgG1Fc protein
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported applications (for relevant formats) include: immunohistochemical staining of frozen tissue sections1 and Western blotting1.

Application References

(PubMed link indicates BioLegend citation)
  1. Park CG, et al. 2012. J. Immunol. Methods 377:15. (IHC, WB)
Product Citations
  1. Sawanobori Y, et al. 2021. Histochem Cell Biol. 156:133. PubMed
  2. Yang P et al. 2019. Cell Syst. 8(5):427-445 . PubMed
RRID
AB_2562438 (BioLegend Cat. No. 359203) AB_2562439 (BioLegend Cat. No. 359204)

Antigen Details

Structure
An N-terminal cysteine-rich domain, a fibronectin type II domain and a series of 10 tandemnly repeated C-type like domains (CTLDs)
Distribution

Expressed at high levels by dendritic cells and thymic epithelial cells; also expressed by B lymphocytes, macrophages, Langerhans cells, bone marrow cells, and epithelial cells

Function
Mediates endocytosis, antigen uptake, presentation, and cross-presentation to T cells
Cell Type
B cells, Dendritic cells, Epithelial cells, Langerhans cells, Macrophages
Biology Area
Immunology, Innate Immunity
Molecular Family
CD Molecules
Antigen References

1. Jiang W, et al. 1995. Nature 375:151.
2. Small M and Kraal G. 2003. Int. Immunol. 15:197.
3. Shrimpton RE, et al. 2009. Mol. Immunol. 46:1229.

Gene ID
4065 View all products for this Gene ID 17076 View all products for this Gene ID 499800 View all products for this Gene ID
UniProt
View information about CD205 on UniProt.org

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