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APC/Cyanine7 anti-human CD14 Antibody
产品名称:
APC/Cyanine7 anti-human CD14 Antibody
产品类别:
抗体
产品编号:
325619
产品应用:
325619
[价格]
规格 价格 库存
25tests ¥ 1836 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography, and conjugated with APC/Cyanine7 under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser
Red Laser (633 nm)
Application Notes

Additional reported applications (for the relevant formats) include: immunofluorescence microscopy. This clone was tested in-house and does not work on formalin fixed paraffin-embedded (FFPE) tissue.

Additional Product Notes
BioLegend is in the process of converting the name APC/Cy7 to APC/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our APC/Cyanine7 products. Please contact Technical Service if you have any questions.
Application References

(PubMed link indicates BioLegend citation)
  1. McMichael A, et al. 1987. Leucocyte Typing III. Oxford University Press. New York.
  2. Knapp W, et al. Eds. 1989. Leucocyte Typing IV. Oxford University Press. New York.
  3. Schlossman S, et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York.
Product Citations
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  6. Manukyan G, et al. 2020. Auto Immun Highlights. 11:5. PubMed
  7. Rajasekhar M, et al. 2017. J Autoimmun. 10.1016/j.jaut.2017.01.002. PubMed
  8. AC Belkina, JE Snyder-Cappione 2017. Cytometry A. 91:175-179. PubMed
  9. Soriano-Sarabia N, et al. 2012. J Immunol. 189:5212. PubMed
  10. Palamides P, et al. 2016. Dis Model Mech. 9: 985 - 997. PubMed
  11. Hagen SH, et al. 2020. Cell Rep. 33:108485. PubMed
  12. Yang Z, et al. 2018. Front Immunol. 9:2613. PubMed
  13. Weisberg SP, et al. 2020. Cell Reports. 29(12):3916-3932.e5.. PubMed
  14. Liu C, et al. 2021. Cell Res. 31:1106. PubMed
  15. Tiwari-Heckler S, et al. 2021. Cell Rep. 37:109897. PubMed
  16. Zhou Y, et al. 2017. Front Cell Infect Microbiol. 7:457. PubMed
  17. Nicholas DA et al. 2019. Cell Metab. 30(3):447-461 . PubMed
  18. Ma YV, et al. 2021. MAbs. 13:2003281. PubMed
  19. Cui L, et al. 2021. Am J Reprod Immunol. 86:e13436. PubMed
  20. Moquin-Beaudry G, et al. 2022. Cell Rep Methods. 2:100153. PubMed
  21. Kuebler P, et al. 2015. Proc Natl Acad Sci U S A. 112: 8379 - 8384. PubMed
  22. Evans RDR, et al. 2020. Nat Commun. 3.491666667. PubMed
  23. Bharath LP, et al. 2020. Cell Metabolism. 32(1):44-55.e6.. PubMed
  24. Schr?der M, et al. 2016. PLoS One. 11: 0157387. PubMed
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  26. Markman JL, et al. 2020. Nat Commun. 11:1613. PubMed
  27. Kacherovsky N, et al. 2019. Nat Biomed Eng. 0.66875. PubMed
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  29. Port JR, et al. 2020. J Virol. 94:. PubMed
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  31. Samarani S, et al. 2020. Mediators Inflamm. 2020:6401969. PubMed
  32. Zhuang Q, et al. 2021. Front Pharmacol. 12:706580. PubMed
  33. Bravo-Flores E, et al. 2018. Int J Mol Sci. 19:E1074. PubMed
  34. Roy Chowdhury R, et al. 2018. Nature. 560:644. PubMed
  35. Ravenhill BJ, et al. 2020. Sci Rep. 10:4560. PubMed
  36. K?rner C et al. 2017. Cell host & microbe. 22(1):111-119 . PubMed
  37. Nakajima S, et al. 2021. Mol Cancer Res. 19:1085. PubMed
  38. Kubala MH, et al. 2018. Cell Rep. 25:2177. PubMed
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RRID
AB_830692 (BioLegend Cat. No. 325619) AB_830693 (BioLegend Cat. No. 325620)

Antigen Details

Structure
GPI-linked membrane glycoprotein, 53-55 kD
Distribution

Monocytes, macrophages, granulocytes (low)

Function
LPS receptor, clearance of Gram-negative pathogens
Ligand/Receptor
LPS
Cell Type
Granulocytes, Macrophages, Monocytes, Neutrophils
Biology Area
Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience
Molecular Family
CD Molecules
Antigen References

1. Stocks S, et al. 1990. Biochem. J. 268:275.
2. Wright S, et al. 1990. Science 249:1434.

Gene ID
929 View all products for this Gene ID
UniProt
View information about CD14 on UniProt.org

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