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APC anti-human CD14 Antibody
产品名称:
APC anti-human CD14 Antibody
产品类别:
抗体
产品编号:
325607
产品应用:
325607
[价格]
规格 价格 库存
25tests ¥ 1644 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser
Red Laser (633 nm)
Application Notes

Additional reported applications (for the relevant formats) include: immunofluorescence microscopy. This clone was tested in-house and does not work on formalin fixed paraffin-embedded (FFPE) tissue.

Application References

(PubMed link indicates BioLegend citation)
  1. McMichael A, et al. 1987. Leucocyte Typing III. Oxford University Press. New York.
  2. Knapp W, et al. Eds. 1989. Leucocyte Typing IV. Oxford University Press. New York.
  3. Schlossman S, et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York.
Product Citations
  1. Colonna L, et al. 2016. Clin Immunol. 163:84-90. PubMed
  2. Guo X, et al. 2016. Mol Ther Methods Clin Dev. 3:15054. PubMed
  3. Xun X, et al. 2021. Am J Transl Res. 13:4360. PubMed
  4. Lamichhane R, et al. 2020. Eur J Immunol. 50:178. PubMed
  5. Hearnden R, et al. 2021. STAR Protocols. 2(2):100422. PubMed
  6. Allegrezza M, et al. 2016. Cancer Res . 76: 6253 - 6265. PubMed
  7. Wang E, et al. 2021. Cell Stem Cell. 28(4):718-731.e6. PubMed
  8. Zhong J, et al. 2018. Sci Adv. 4:eaas9864. PubMed
  9. Schepp J, et al. 2017. Arthritis Rheumatol. 69:1689. PubMed
  10. Liu Y, et al. 2021. Front Immunol. 11:579372. PubMed
  11. Wang Y, et al. 2021. Sci Rep. 1.429861111. PubMed
  12. Keller M, et al. 2013. PLoS One. 12:79601. PubMed
  13. Collins D, et al. 2015. PLoS Pathog. 11: 1005054. PubMed
  14. Pellegrini JM, et al. 2021. Sci Rep. 11:13559. PubMed
  15. Fu W, et al. 2016. Sci Rep. 6:38162. PubMed
  16. Fisch D, et al. 2022. Pathog Dis. 79:. PubMed
  17. Rohner L, et al. 2020. Sci Rep. 0.570833333. PubMed
  18. Hakimi AA, et al. 2019. Cancer Discov. 9:510. PubMed
  19. Zhu Y, et al. 2019. Cell Stem Cell. 25:542. PubMed
  20. Vabret N, et al. 2022. iScience. 25:104599. PubMed
  21. Akoumianaki T, et al. 2021. Cell Host Microbe. . PubMed
  22. Fujisaka Y, et al. 2018. Oncol Lett. 15:509. PubMed
  23. Li YR, et al. 2021. Cell Rep Med. 2:100449. PubMed
  24. Molina MS, et al. 2021. Front Immunol. 12:699128. PubMed
  25. Domanska D, et al. 2022. J Exp Med. 219:. PubMed
  26. Wee Y, et al. 2016. Exp Biol Med. 241: 1217 - 1228. PubMed
  27. Cointe S, et al. 2018. J Extracell Vesicles. 7:1494482. PubMed
RRID
AB_830680 (BioLegend Cat. No. 325607) AB_830681 (BioLegend Cat. No. 325608)

Antigen Details

Structure
GPI-linked membrane glycoprotein, 53-55 kD
Distribution

Monocytes, macrophages, granulocytes (low)

Function
LPS receptor, clearance of Gram-negative pathogens
Ligand/Receptor
LPS
Cell Type
Granulocytes, Macrophages, Monocytes, Neutrophils
Biology Area
Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience
Molecular Family
CD Molecules
Antigen References

1. Stocks S, et al. 1990. Biochem. J. 268:275.
2. Wright S, et al. 1990. Science 249:1434.

Gene ID
929 View all products for this Gene ID
UniProt
View information about CD14 on UniProt.org

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