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Alexa Fluor® 700 anti-human CD14 Antibody
产品名称:
Alexa Fluor® 700 anti-human CD14 Antibody
产品类别:
抗体
产品编号:
325614
产品应用:
325614
[价格]
规格 价格 库存
100µg ¥ 3180 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 700 under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤2.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.


Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.

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Excitation Laser
Red Laser (633 nm)
Application Notes

Additional reported applications (for the relevant formats) include: immunofluorescence microscopy. This clone was tested in-house and does not work on formalin fixed paraffin-embedded (FFPE) tissue.

Application References

(PubMed link indicates BioLegend citation)
  1. McMichael A, et al. 1987. Leucocyte Typing III. Oxford University Press. New York.
  2. Knapp W, et al. Eds. 1989. Leucocyte Typing IV. Oxford University Press. New York.
  3. Schlossman S, et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York.
Product Citations
  1. Iwahori K, et al. 2019. Sci Rep. 2.205555556. PubMed
  2. Carre C, et al. 2021. iScience. 24:102970. PubMed
  3. Li M, et al. 2021. J Clin Invest. 131:. PubMed
  4. Hasaart KAL, et al. 2020. Sci Rep. 10:12991. PubMed
  5. Kang L, et al. 2020. Exp Hematol Oncol. 9:11. PubMed
  6. ?ngela Crespo, Jack Strominger, Tamara Tilburgs 2016. Proc Natl Acad Sci U S A. 113(52):15072-15077. PubMed
  7. Perelman SS, et al. 2021. Nat Microbiol. 6:731. PubMed
  8. Shin J, et al. 2012. Nucleic Acids Res. 40:165. PubMed
  9. Heger L, et al. 2018. Front Immunol. 9:744. PubMed
  10. Martín–Gayo E, et al. 2020. Cell Rep. 30:984. PubMed
  11. Agashe VV, et al. 2018. J Immunol. 201:772. PubMed
  12. Lee YS, et al. 2021. J Immunother Cancer. 9:. PubMed
  13. Turner JS, et al. 2020. Nature. 586:127. PubMed
  14. Mackroth M, et al. 2016. PLoS Pathog. 12:e1005909. PubMed
  15. Teng F, et al. 2021. Cell Rep. 37:110051. PubMed
  16. Harris LD, et al. 2020. Front Cell Infect Microbiol. 10:120. PubMed
  17. Al-ofi E, et al. 2012. PLoS One. 7:e42217. PubMed
RRID
AB_830687 (BioLegend Cat. No. 325614)

Antigen Details

Structure
GPI-linked membrane glycoprotein, 53-55 kD
Distribution

Monocytes, macrophages, granulocytes (low)

Function
LPS receptor, clearance of Gram-negative pathogens
Ligand/Receptor
LPS
Cell Type
Granulocytes, Macrophages, Monocytes, Neutrophils
Biology Area
Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience
Molecular Family
CD Molecules
Antigen References

1. Stocks S, et al. 1990. Biochem. J. 268:275.
2. Wright S, et al. 1990. Science 249:1434.

Gene ID
929 View all products for this Gene ID
UniProt
View information about CD14 on UniProt.org

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