APC anti-human C3AR Antibody
- 产品名称：
- APC anti-human C3AR Antibody
- 产品类别：
- 抗体
- 产品编号：
- 345805
- 产品应用：
- 345805
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1848 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- hC3aR transfected cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Red Laser (633 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen sections2.
- Application References
(PubMed link indicates BioLegend citation) -
- Soruri A, et al. 2002. J. Immunol. 170:3306 (FC)
- Kiafard Z, et al. 2007 Immunobiology. 212:129 (FC, IHC)
- RRID
- AB_10899735 (BioLegend Cat. No. 345805) AB_10899569 (BioLegend Cat. No. 345806)
- Structure
- 482 aa, single chain protein with seven membrane-spanning regions, 54 kD
- Distribution
-
Neutrophils, eosinophils, mast cells, monocytes, dendritic cells, hematopoietic and mesenchymal stem cells, endothelial cells
- Function
- After C3a binding, the C3AR signaling results in chemotaxis, granule enzyme release and superoxide anion production.
- Interaction
- G proteins
- Bioactivity
- Chemotaxis, degranulation
- Cell Type
- Dendritic cells, Endothelial cells, Eosinophils, Mast cells, Mesenchymal Stem Cells, Monocytes, Neutrophils
- Biology Area
- Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity, Neuroinflammation, Neuroscience, Stem Cells
- Molecular Family
- Cytokine/Chemokine Receptors
- Antigen References
-
1. Wysoczynski M et al. 2009. Leukemia. 23:1455
2. Schraufstatter IU. et al. 2009. J. Immunol. 182:3827
3. Honczarenko M et al. 2005. J. Immunol. 175:3698
4. Reca R et al. 2003. Blood 101:3784
- Gene ID
- 719 View all products for this Gene ID
- UniProt
- View information about C3aR on UniProt.org
