Purified anti-human ANTXR2 Antibody
- 产品名称：
- Purified anti-human ANTXR2 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 318402
- 产品应用：
- 318402
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- HCC827 GR2 cell line
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 ?g per million cells in 100 ?L volume. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2876621 (BioLegend Cat. No. 318402)
- Structure
- Type I transmembrane protein, with an extracellular van Willebrand factor A (vWA) domain, an Ig-like domain, a single transmembrane helix and a cytoplasmic tail. 54 kD.
- Distribution
-
ANTXR2 is expressed on T cell, B cell, dendritic cell, monocytes, and granulocytes.
- Function
- The ANTXR2 protein acts as a receptor for the toxin that causes anthrax, allowing the toxin to attach to cells and trigger disease. The ANTXR2 protein is also involved in the formation of capillaries and maintaining the structure of basement membranes.
- Ligand/Receptor
- Protective antigen (PA), laminin, collagen type IV
- Cell Type
- B cells, Dendritic cells, Granulocytes, Monocytes, T cells
- Biology Area
- Bacterial proteins and Toxins
- Molecular Family
- Adhesion Molecules
- Antigen References
-
- Burgi J, et al. 2017. Nature Comms. 8:15861
- Scobie H, et al. 2003. Proc. Natl. Acad. Sci. USA. 100:5170
- Gene ID
- 118429 View all products for this Gene ID
- UniProt
- View information about ANTXR2 on UniProt.org
