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Biotin anti-human CD63 Antibody
产品名称:
Biotin anti-human CD63 Antibody
产品类别:
抗体
产品编号:
353017
产品应用:
353017
[价格]
规格 价格 库存
50µg ¥ 1068 1

产品详情

Product Details

Verified Reactivity
Human
Reported Reactivity
African Green, Baboon, Cynomolgus, Rhesus
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
T cell line HPB-ALL
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography and conjugated with biotin under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported applications (for the relevant formats) include: Western blotting1, immunofluorescence2, and immunoprecipitation1.

Application References

(PubMed link indicates BioLegend citation)
  1. Hildreth JE, et al. 1991. Blood 77:121. (IP, WB)
  2. Beatty WL, et al. 2006. J. Cell Sci. 119:350. (IF)
Product Citations
  1. Kolan S, et al. 2015. Biochem Biophys Res Commun. 460:645. PubMed
  2. Yildizhan Y, et al. 2021. J Extracell Vesicles. e12059:10. PubMed
  3. Suthar J, et al. 2020. Anal Chem. 92:4082. PubMed
  4. Theodoraki MN, et al. 2018. Clin Cancer Res. 24:896. PubMed
  5. Wang J, et al. 2020. Sci Adv. 6:eaax3223. PubMed
  6. Theodoraki MN, et al. 2020. Oncoimmunology. 9:1747732. PubMed
  7. Kim D, et al. 2016. Proc Natl Acad Sci U S A. 113: 170 - 175. PubMed
  8. Zheng W, et al. 2022. Nat Biomed Eng. 6:979. PubMed
  9. Turiello R, et al. 2022. J Immunother Cancer. 10:. PubMed
  10. Theodoraki MN, et al. 2021. Br J Cancer. 125:1677. PubMed
  11. K?ksal AR, et al. 2022. J Hepatocell Carcinoma. 9:959. PubMed
  12. Priglinger E, et al. 2021. J Extracell Vesicles. 10:e12156. PubMed
  13. Hofmann L, et al. 2022. Front Med (Lausanne). 9:904295. PubMed
  14. Hofmann L, et al. 2020. Int J Mol Sci. 21:00. PubMed
  15. Mondal SK, et al. 2021. Methods Mol Biol. 2265:305. PubMed
RRID
AB_2561675 (BioLegend Cat. No. 353017) AB_2561676 (BioLegend Cat. No. 353018)

Antigen Details

Structure
Tetraspan transmembrane superfamily (TM4SF), type III lysosomal glycoprotein, 53 kD
Distribution

Activated platelets, monocytes, macrophages, endothelium, fibroblasts, osteoclasts, and smooth muscle

Function
Platelet activation
Interaction
CD9, CD81, VLA-3, and VLA-6
Cell Type
B cells, Endothelial cells, Fibroblasts, Macrophages, Monocytes, Osteoclasts, Platelets
Biology Area
Cell Adhesion, Cell Biology, Immunology
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References
  1. Azorsa DO, et al. 1991. Blood 78:280.
  2. Kishimoto T, et al. Eds. 1997. Leukocyte Typing V1. Oxford University Press New York.
  3. Hildreth JE, et al. 1991. Blood 77:121.
  4. Anzai N, et al. 2002. Blood 99:4413.
Gene ID
967 View all products for this Gene ID
UniProt
View information about CD63 on UniProt.org

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