Alexa Fluor® 594 anti-human CD107b (LAMP-2) An-上海雅吉生物科技有限公司

规格	价格	库存
25µg	￥ 1908	1

Product Details

Verified Reactivity

Human

Antibody Type

Monoclonal

Host Species

Mouse

Immunogen

Adult human adherent spleen cells

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation

The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 594 under optimal conditions.

Concentration

0.5 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

IHC-P - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 5 - 10 ?g/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.

* Alexa Fluor? 594 has an excitation maximum of 590 nm, and a maximum emission of 617 nm.

Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.

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Application Notes

Additional reported applications (for the relevant formats) include: immunohistochemical staining of frozen glomeruli² and immunofluorescent staining of ?neutrophils^2,3.

This antibody is specific to human LAMP-2. Positive control: Hela cells; LAMP-2 molecular weight appears to be at ~110 kDa on the gel due to high glycosylation.

Application References (PubMed link indicates BioLegend citation)

Chen J, et al. 1985. J. Biol. Chem. 101:85.
Kain R, et al. 2008. Nat. Med. 14:1088. (IF, IHC)
Roark EA, et al. 2008. PLoS ONE 3:e3538. (IF)

RRID

AB_2721377 (BioLegend Cat. No. 354309) AB_2721378 (BioLegend Cat. No. 354310)

Antigen Details

Structure: LAMP-2 is a 410 amino acid protein with a molecular mass of 45 kD.
Distribution: Lysosomal/endosomal membranes in nearly all cells; surface of activated platelets, activated lymphocytes and some tumor cell lines
Function: Adhesion, cellular homeostatis, including autophagocytosis, antigen presentation
Cell Type: B cells, Lymphocytes, Platelets
Biology Area: Cell Adhesion, Cell Biology, Cell Motility/Cytoskeleton/Structure, Immunology, Innate Immunity, Neurodegeneration, Neuroscience, Protein Trafficking and Clearance
Molecular Family: Adhesion Molecules, CD Molecules
Antigen References: 1. Chen J,?et al.?1985.?J. Biol. Chem.?101:85.
2. Kain R,?et al.?2008.?Nat. Med. 14:1088.
3. Roark EA,?et al.?2008.?PLoS ONE?3:e3538.
Gene ID: 3920 View all products for this Gene ID
UniProt: View information about CD107b on UniProt.org

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