Purified anti-human CD107a (LAMP-1) (Maxpar® R-上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 1692	1

Product Details

Verified Reactivity

Human

Reported Reactivity

African Green, Baboon, Chimpanzee, Cynomolgus, Pigtailed Macaque, Rhesus

Antibody Type

Monoclonal

Host Species

Mouse

Immunogen

Human adult adherent peripheral blood cells

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA.

Preparation

The antibody was purified by affinity chromatography.

Concentration

1.0 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C.

Application

FC - Quality tested
CyTOF? - Verified

Recommended Usage

This product is suitable for use with the?Maxpar? Metal Labeling Kits.?For metal labeling using Maxpar? Ready antibodies,?proceed directly to the step to Partially Reduce the Antibody by adding 100 ?l of Maxpar? Ready antibody to 100 ?l of 4 mM TCEP-R in a 50 kDa filter and continue with the protocol. Always refer to the latest version of Maxpar? User Guide when conjugating Maxpar? Ready antibodies.

Application Notes

Additional reported applications (for the relevant formats) include: Western blotting⁸, immunohistochemical staining², immunofluorescence^5,7, and immunoprecipitation⁵.

This antibody is specific to human LAMP-1. Positive control: Hela cells; LAMP-1 molecular weight appears to be at ~110 kDa on the gel due to high glycosylation.

Additional Product Notes

Maxpar? is a registered trademark of Standard BioTools Inc.

Application References (PubMed link indicates BioLegend citation)

Misse D, et al. 1999. Blood 93:2454.
Furuta K, et al. 2001. Am. J. Pathol. 159:449. (IHC)
Watanabe A, et al. 2011. J. Biol. Chem. 286:10702. PubMed
Baron Gaillard CL, et al. 2011. Mol. Cell. Biol. 22:5459. PubMed
Hauck CR and Meyer TF. 1997. FEBS Lett. 405:86. (IF, IP)
De Keersmaecker B, et al. 2012. J. Virol. 86:9351. PubMed
Knodler LA, et al. 2010. P. Natl. Acad. Sci. USA. 107:17733. (IF)
Oh J, et al. 2000. Hum. Mol. Genet. 9:375. (WB)
Salio M, et al. 2013 PNAS. 110:4753. PubMed

RRID

AB_2563708 (BioLegend Cat. No. 328635)

Antigen Details

Structure: LAMP-1 is a 417 amino acid protein with a molecular mass of 45 kD.
Distribution: Macrophages, epithelial cells, endothelial cells, some tumor cells; located on the luminal side of lysosomes or on the surface of cell membranes
Function: Protect lysosomal membrane from lysosomal hydrolases, adhesion
Ligand/Receptor: Galaptin
Cell Type: Endothelial cells, Epithelial cells, Macrophages
Biology Area: Cell Biology, Immunology, Neurodegeneration, Neuroscience, Protein Trafficking and Clearance
Molecular Family: Adhesion Molecules, CD Molecules
Antigen References: 1. Sarafian V, et al. 2006. Arch. Dermatol. Res. 298:7381.
2. Schlossman SF, et al. 1995. Leukocyte Typing V:White Cell Differentiation Antigens. New York:Oxford University Press.
3. Sawada R, et al. 1993. J. Biol. Chem. 268:12675.
4. Chen JW, et al. 1988. J. Biol. Chem. 263:8754.
5. Chen JW, et al. 1986. Biochem. Soc. Symp. 51:97112.
Gene ID: 3916 View all products for this Gene ID
UniProt: View information about CD107a on UniProt.org

上海细胞库

原代细胞

细胞培养

细胞服务

酶联试剂盒

生化试剂盒

PCR试剂盒

抗体蛋白

试剂耗材

首页 > 抗体蛋白 > 抗体

产品详情

Product Details

Antigen Details

联系我们