热线电话: 021-34661275
产品分类/PRODUCT CLASSIFICATION

上海细胞库

人源细胞系| 稳转细胞系| 基因敲除株| 基因点突变细胞株| 基因过表达细胞株| 重组细胞系| 猪的细胞系| 马细胞系| 兔的细胞系| 犬的细胞系| 山羊的细胞系| 鱼的细胞系| 猴的细胞系| 仓鼠的细胞系| 狗的细胞系| 牛的细胞| 大鼠细胞系| 小鼠细胞系| 其他细胞系|

原代细胞

原代细胞| 永生化细胞|

细胞培养

血清| 无血清冻存| 细胞培养试剂盒| 普通培养基| 完全培养基| 细胞污染预防| 细胞污染清除| 细胞培养辅助试剂|

细胞服务

STR鉴定服务| ATCC代购服务|

酶联试剂盒

人ELISA试剂盒| 大鼠ELISA试剂盒| 小鼠ELISA试剂盒| 兔ELISA试剂盒| 猪ELISA试剂盒| 鱼ELISA试剂盒| 牛ELISA试剂盒| 犬ELISA试剂盒| 鸭ELISA试剂盒| 豚鼠ELISA试剂盒| 鸡ELISA试剂盒| 绵羊ELISA试剂盒| 山羊ELISA试剂盒| 仓鼠ELISA试剂盒| 植物ELISA试剂盒| 药残留类试剂盒| 其他ELISA试剂盒|

生化试剂盒

生化试剂盒| 微量法检测盒| 分光法检测盒| 胶体金检测盒|

PCR试剂盒

荧光探针PCR试剂盒| 染料荧光PCR试剂盒| 核酸扩增/纯化| 普通PCR检测试剂盒| 质粒菌种感受态|

抗体蛋白

蛋白多肽| 抗体| 免疫组化| 免疫球蛋白|

试剂耗材

标准试液| 科研试剂| 缓 冲 液| 实验耗材| 高效液相色谱对照品|

首页 > 抗体蛋白 > 抗体
PE anti-human CD107a (LAMP-1) Antibody
产品名称：
PE anti-human CD107a (LAMP-1) Antibody
产品类别：
抗体
产品编号：
328607
产品应用：
328607
[价格]
规格 价格 库存
25tests ￥ 1296 1

产品详情

Product Details

Verified Reactivity
Human
Reported Reactivity
African Green, Baboon, Chimpanzee, Cynomolgus, Pigtailed Macaque, Rhesus
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Human adult adherent peripheral blood cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported applications (for the relevant formats) include: Western blotting8, immunohistochemical staining2, immunofluorescence5,7, and immunoprecipitation5.

This antibody is specific to human LAMP-1. Positive control: Hela cells; LAMP-1 molecular weight appears to be at ~110 kDa on the gel due to high glycosylation.

Application References

(PubMed link indicates BioLegend citation)
  1. Misse D, et al. 1999. Blood 93:2454.
  2. Furuta K, et al. 2001. Am. J. Pathol. 159:449. (IHC)
  3. Watanabe A, et al. 2011. J. Biol. Chem. 286:10702. PubMed
  4. Baron Gaillard CL, et al. 2011. Mol. Cell. Biol. 22:5459. PubMed
  5. Hauck CR and Meyer TF. 1997. FEBS Lett. 405:86. (IF, IP)
  6. De Keersmaecker B, et al. 2012. J. Virol. 86:9351. PubMed
  7. Knodler LA, et al. 2010. P. Natl. Acad. Sci. USA. 107:17733. (IF)
  8. Oh J, et al. 2000. Hum. Mol. Genet. 9:375. (WB)
  9. Salio M, et al. 2013 PNAS. 110:4753. PubMed
Product Citations
  1. Willcox CR, et al. 2020. Immunity. 51(5):813-825.e4.. PubMed
  2. Liu R, et al. 2022. Aging Dis. 13:1576. PubMed
  3. Afolabi LO, et al. 2021. Front Immunol. 12:701671. PubMed
  4. Lamichhane R, et al. 2020. Eur J Immunol. 50:178. PubMed
  5. Chen D, et al. 2021. Dev Cell. 56:3250. PubMed
  6. Kim JT, et al. 2022. Nat Commun. 13:121. PubMed
  7. Gao Y, et al. 2021. Oncogenesis. 10:62. PubMed
  8. Izumi K, et al. 2021. Immunohorizons. 5:687. PubMed
  9. Stevenson EM, et al. 2022. Nat Commun. 13:4888. PubMed
  10. Karampatzakis A, et al. 2021. Front Immunol. 12:641521. PubMed
  11. Ping Y, et al. 2020. Front Cell Dev Biol. 0.890972222. PubMed
  12. Sibener LV et al. 2018. Cell. 174(3):672-687 . PubMed
  13. Chandran P, et al. 2014. J Leukoc Biol. 96:633. PubMed
  14. Laroni A, et al. 2016. J Autoimmun. 72:8-18. PubMed
  15. Palazzo A, et al. 2018. J Immunol. 200:2304. PubMed
  16. Yao X, et al. 2020. Adv Sci (Weinh). 7:1902938. PubMed
  17. Su X, et al. 2022. J Transl Med. 20:378. PubMed
  18. Schanin J, et al. 2022. Commun Biol. 5:1226. PubMed
  19. Castro I, et al. 2016. J Virol. 90: 5280 - 5291. PubMed
  20. Pugsley H, et al. 2017. Methods. 112:147-156. PubMed
  21. Oyer JL, et al. 2022. Front Immunol. 13:861681. PubMed
  22. Hirama T, et al. 2021. JCI Insight. 6:. PubMed
  23. Lettau M, et al. 2018. Int Immunol. 30:215. PubMed
  24. Pollack RA, et al. 2017. Cell Host Microbe. 1.218055556. PubMed
  25. Li Y, et al. 2022. J Immunol. 208:347. PubMed
  26. Heard A, et al. 2022. Nat Commun. 13:3367. PubMed
  27. Pahl JHW, et al. 2018. Cancer Immunol Res. 0.609027778. PubMed
  28. Mathewson ND, et al. 2021. Cell. 184(5):1281-1298.e26. PubMed
  29. Katsuyama E, et al. 2020. Cell Reports. 30(1):112-123.e4.. PubMed
  30. Gambacorta V, et al. 2022. Cancer Discov. . PubMed
  31. Pomplun NL, et al. 2021. Cytometry A. 99:278. PubMed
  32. Christensen SR, et al. 2019. J Virol. 93:8. PubMed
  33. Liu CF, et al. 2017. Front Immunol. 1.445833333. PubMed
  34. Plum T, et al. 2020. Immunity. 52(2):404-416. PubMed
  35. Mo YQ, et al. 2022. J Clin Invest. . PubMed
  36. Shen C, et al. 2021. BMC Med. 19:283. PubMed
  37. Li M, et al. 2020. Virol Sin. 35:588. PubMed
  38. Sadallah S, et al. 2016. J Immunol. 197: 1663 - 1671. PubMed
  39. Huang W, et al. 2012. Cell Res. 22:473. PubMed
  40. Lamichhane R et al. 2019. Cell Rep. 28(12):3061-3076 . PubMed
  41. Chen PM, et al. 2022. Sci Adv. 8:eabo4271. PubMed
RRID
AB_1186062 (BioLegend Cat. No. 328607) AB_1186040 (BioLegend Cat. No. 328608)

Antigen Details

Structure
LAMP-1 is a 417 amino acid protein with a molecular mass of 45 kD.
Distribution

Macrophages, epithelial cells, endothelial cells, some tumor cells; located on the luminal side of lysosomes or on the surface of cell membranes

Function
Protect lysosomal membrane from lysosomal hydrolases, adhesion
Ligand/Receptor
Galaptin
Cell Type
Endothelial cells, Epithelial cells, Macrophages
Biology Area
Cell Biology, Immunology, Neurodegeneration, Neuroscience, Protein Trafficking and Clearance
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Sarafian V, et al. 2006. Arch. Dermatol. Res. 298:7381.
2. Schlossman SF, et al. 1995. Leukocyte Typing V:White Cell Differentiation Antigens. New York:Oxford University Press.
3. Sawada R, et al. 1993. J. Biol. Chem. 268:12675.
4. Chen JW, et al. 1988. J. Biol. Chem. 263:8754.
5. Chen JW, et al. 1986. Biochem. Soc. Symp. 51:97112.

Gene ID
3916 View all products for this Gene ID
UniProt
View information about CD107a on UniProt.org

联系我们

TEL：021-34661275 　点击拨打热线