FITC anti-mouse CD26 (DPP-4) Antibody
- 产品名称：
- FITC anti-mouse CD26 (DPP-4) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 137805
- 产品应用：
- 137805
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- BALB/c thymocytes
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume.? It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
- Application Notes
Additional reported applications include: in vitro activation of thymocytes1, immunoprecipitation from cell lysates and cell-free supernatants1,2 and immunohistochemical staining of frozen tissue sections1.
- Application References
(PubMed link indicates BioLegend citation) -
- Naquet P, et al. 1988. J. Immunol. 141:4101.
- Vivier I, et al. 1991. J. Immunol. 147:447.
- Sen A, et al. 2012. PNAS PubMed
- Coleman CM, et al. 2014. J Gen Virol. 95:408. PubMed
- Product Citations
-
- Hutton C, et al. 2021. Cancer Cell. 39:1227. PubMed
- Stefkovich M, et al. 2021. Mol Metab. 54:101357. PubMed
- Duarte N, et al. 2018. Hepatol Commun. 0.833333333. PubMed
- Clemente–Casares X, et al. 2017. Immunity. 47:974. PubMed
- Lerbs T, et al. 2020. JCI Insight. 5:00. PubMed
- Giles DA, et al. 2018. J Clin Invest. 128:5322. PubMed
- Deniset JF et al. 2019. Immunity. 51(1):131-140 . PubMed
- RRID
- AB_10662380 (BioLegend Cat. No. 137805) AB_10663402 (BioLegend Cat. No. 137806)
- Structure
- Homodimer, each monomer is a single chain type II transmembranal molecule of 110 kD that consists of two domains; soluble form is released after proteolysis of the membrane form
- Distribution
-
Mature thymocytes, activated T cells, B cells, NK cells, macrophages
- Function
- T cell costimulation, endothelial cell migration, proteolysis
- Interaction
- CAV1, IGF2R, PTPRC, BCL10, CARD1, IKBKB
- Ligand/Receptor
- ADA, collagen
- Cell Type
- B cells, Macrophages, NK cells, T cells, Thymocytes
- Biology Area
- Immunology, Costimulatory Molecules
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Cooper KG, et al. 2009. Infect. Immun. 77:2447.
2. Eltzschig HK, et al. 2006. Blood 108:1602.
3. Peranteau WH, et al. 2006. Blood 108:4268.
- Gene ID
- 13482 View all products for this Gene ID
- UniProt
- View information about CD26 on UniProt.org
