首页 > 抗体蛋白 > 抗体
PE anti-mouse CD69 Antibody
产品名称:
PE anti-mouse CD69 Antibody
产品类别:
抗体
产品编号:
104507
产品应用:
104507
[价格]
规格 价格 库存
50µg ¥ 1464 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Armenian Hamster
Immunogen
Mouse dendritic epidermal T cell line Y245
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

The H1.2F3 antibody has been reported to augment T cell activation. Additional reported applications (for the relevant formats) include: in vitro T cell and NK cell activation1-3, immunohistochemistry4,5, and immunoprecipitation1.

This antibody has been characterized in the literature as containing a lambda (?) light chain.

Application References

(PubMed link indicates BioLegend citation)
  1. Yokoyama WM, et al. 1988. J. Immunol. 141:369. (IP)
  2. Sobel ES, et al. 1993. J. Immunol. 150:673.
  3. Karlhofer FM, et al. 1991. J. Immunol. 146:3662.
  4. Zhou X, et al. 2005. J. Biol. Chem. 280:31240. (IHC)
  5. Podd BS, et al. 2006. J. Immunol. 176:6532. (IHC)
  6. Lawson BR, et al. 2007. J. Immunol. 178:5366.
  7. Lee JW, et al. 2006. Nature Immunol. 8:181.
  8. Epardaud M, et al. 2008. Cancer Res. 15:2972. PubMed
  9. Jordan JM, et al. 2008. 76:3717. PubMed
  10. Kenna TJ, et al. 2008. Blood 111:2091. PubMed
  11. Ishikawa C, et al. 2013. Biochim Biophys Acta. 167:99. PubMed
Product Citations
  1. Yuan Z, et al. 2011. Vaccine. 29:6614. PubMed
  2. D'Alessandro G, et al. 2020. Eur J Immunol. 50:705. PubMed
  3. Lin C, et al. 2020. Cancer Immunol Res. 632:8. PubMed
  4. Glasner A,et al. 2017. Sci Rep.. 10.1038/s41598-017-12998-w. PubMed
  5. Toubai T, et al. 2017. Blood Adv. 1.095138889. PubMed
  6. Dong MB, et al. 2020. Cell. 178(5):1189-1204.e23.. PubMed
  7. Shah D, et al. 2021. Oncoimmunology. 10:1939601. PubMed
  8. Chen N, et al. 2021. Front Immunol. 12:756423. PubMed
  9. Bian L, et al. 2022. Front Immunol. 13:938598. PubMed
  10. Afolabi LO, et al. 2021. Front Immunol. 12:701671. PubMed
  11. Liang S, et al. 2022. Acta Pharm Sin B. 12:2494. PubMed
  12. Mier-Aguilar C, et al. 2016. PLoS One. 11:e0168155. PubMed
  13. Wu J, et al. 2020. Cell Reports. 31(1):107484. PubMed
  14. Zhang H, et al. 2017. Leukemia. 10.1128/mBio.00226-17. PubMed
  15. Alotaibi F, et al. 2021. Front Immunol. 11:584937. PubMed
  16. Achmus L, et al. 2020. Front Neurol. 11:577971. PubMed
  17. Kmieciak M, et al. 2011. Breast Cancer Res Treat. 126:385. PubMed
  18. Bartleson JM, et al. 2020. Nat Immunol. 1384:21. PubMed
  19. Misumi I et al. 2019. Cell Rep. 27(2):514-524 . PubMed
  20. Holan V, et al. 2010. J Immunol. 184:2124. PubMed
  21. Hoffman D, et al. 2021. Immunity. 54:2712. PubMed
  22. Mitchell JE, et al. 2021. Cell Reports. 35(2):108966. PubMed
  23. Guo Z, et al. 2016. Nat Commun. 7:10307. PubMed
  24. Artinger K, et al. 2015. PLoS One. 10: 0135087. PubMed
  25. Velázquez K, et al. 2016. Am J Physiol Gastrointest Liver Physiol. 311: G699 - G712. PubMed
  26. Hu J, et al. 2020. Biomed Pharmacother. 127:110229. PubMed
  27. Caronni N, et al. 2018. Cancer Res. 78:1685. PubMed
  28. Len-Letelier RA, et al. 2020. Frontiers in Immunology. 11:583382. PubMed
  29. Huang Z, et al. 2012. J Immunol. 188:5867. PubMed
  30. Jackstadt R, et al. 2019. Cancer Cell. 36:319. PubMed
  31. Luo W, et al. 2022. Front Immunol. 13:816761. PubMed
  32. Walter F, et al. 2020. PLoS One. 15:e0239369. PubMed
  33. Leylek R, et al. 2019. Cell Rep. 29:3736. PubMed
  34. Hu Q, et al. 2018. Nat Biomed Eng. 0.660416667. PubMed
  35. Suryawanshi RK, et al. 2021. Nat Commun. 12:6020. PubMed
  36. Cheng B, et al. 2022. Cancer Commun (Lond). 42:17. PubMed
  37. Glaros V, et al. 2021. Immunity. 54:2005. PubMed
  38. Brigas HC, et al. 2021. Cell Reports. 36(9):109574. PubMed
  39. Watanabe M, et al. 2020. Nat Commun. 4.808333333. PubMed
  40. Sido J, et al. 2015. J Leukoc Biol. 98: 435-447. PubMed
  41. Place D, et al. 2017. PLoS One. 10.1371/journal.pone.0190384. PubMed
  42. Palazon A, et al. 2017. Cancer Cell. . 10.1016/j.ccell.2017.10.003. PubMed
  43. Trefzer A, et al. 2021. Cell Reports. 34(6):108748. PubMed
  44. Kemp V, et al. 2018. Cancer Gene Ther. 26:268. PubMed
  45. Sendler M, et al. 2020. Gastroenterology. 158:253. PubMed
  46. Wittner J, et al. 2022. Mucosal Immunol. 15:668. PubMed
  47. Frost JN, et al. 2021. Med (N Y). 2:164. PubMed
  48. Daneshmandi S, et al. 2021. Elife. 10:. PubMed
  49. Subramanian K, et al. 2019. Nat Microbiol. 4:62. PubMed
  50. Li D, et al. 2022. Emerg Microbes Infect. 11:2248. PubMed
  51. Kang J, Lee J, Chang J 2016. PLoS One. 11: 0157015. PubMed
  52. X X, et al. 2016. J Immunol . 197: 1683-1691. PubMed
  53. Daneshmandi S, et al. 2021. Cell Reports. 34(10):108831. PubMed
  54. Yan Q, et al. 2017. Molecular Immunology. 10.1016/j.molimm.2017.05.006. PubMed
  55. Skadow M, et al. 2019. J Immunol. 203:370. PubMed
  56. Cartwright ANR, et al. 2021. Cancer Immunol Res. 9:470. PubMed
  57. Passos C, et al. 2014. Food Chem. 15:161. PubMed
  58. Contreras NA, et al. 2019. PLoS Pathog. 15:e1007890. PubMed
  59. van Geffen C, et al. 2021. Front Immunol. 12:695933. PubMed
  60. Jang A, et al. 2015. Life Sci . 135: 138-146. PubMed
  61. Cerina M, et al. 2017. Brain Behav Immun. 59:103-117. PubMed
  62. Tsyklauri O, et al. 2021. EMBO Rep. 22:e50785. PubMed
  63. Lopes N, et al. 2022. Elife. 11:. PubMed
  64. Guo X, et al. 2020. J Cell Mol Med. . PubMed
  65. Charlton J, et al. 2015. PLoS One. 10:119200. PubMed
  66. Han P, et al. 2020. Sci Adv. 6:eaaz1580. PubMed
  67. Amantini C, et al. 2017. Oncotarget. 8:90766. PubMed
  68. Ceglia V, et al. 2021. J Immunol. 207:2060. PubMed
  69. Schulze J, et al. 2021. Stroke. 52:2939. PubMed
  70. Corrado M, et al. 2020. Cell Metab. 32:981. PubMed
  71. Tian T, et al. 2020. Cancer Immunol Res. 660:8. PubMed
  72. Timilshina M, et al. 2020. Cell Reports. 27(10):2948-2961.e7.. PubMed
  73. Yang FM, et al. 2022. Front Immunol. 13:918241. PubMed
  74. Olguín J, et al. 2015. Microbes Infect. 17: 586-595. PubMed
  75. Tsai S, et al. 2018. Cell Metab. 28:922. PubMed
  76. Quijano-Rubio A, et al. 2022. Nat Biotechnol. Online ahead of print. PubMed
RRID
AB_313110 (BioLegend Cat. No. 104507) AB_313111 (BioLegend Cat. No. 104508)

Antigen Details

Structure
C-type lectin, 27/33 kD
Distribution

Activated T cells and B cells, NK cells, granulocytes, thymocytes, platelets

Function
Lymphocyte activation
Cell Type
B cells, Granulocytes, NK cells, Platelets, T cells, Thymocytes, Tregs
Biology Area
Costimulatory Molecules, Immunology, Innate Immunity
Molecular Family
CD Molecules
Antigen References

1. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Testi R, et al. 1994. Immunol. Today 15:479.
3. Moretta A, et al. 1991. J. Exp. Med. 174:1393.
4. Yokoyama WM, et al. 1988. J. Immunol. 141:369.

Gene ID
12515 View all products for this Gene ID
UniProt
View information about CD69 on UniProt.org

联系我们

TEL:021-34661275  点击拨打热线