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Purified anti-mouse CD85k (gp49 Receptor) Antibody
产品名称:
Purified anti-mouse CD85k (gp49 Receptor) Antibody
产品类别:
抗体
产品编号:
144902
产品应用:
144902
[价格]
规格 价格 库存
100µg ¥ 1908 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Armenian Hamster
Immunogen
gp49B-Fc fusion protein
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Clone H1.1 recognizes both gp49A and gp49B. Additional reported applications (for the relevant formats) include in vitro activation of gp49B to inhibit cytokine production.? The LEAF? or Ultra-LEAF? purified antibody is recommended for functional assays (contact our custom solutions team).

Application References

(PubMed link indicates BioLegend citation)
  1. Wang LL, et al. 2000. J. Immunol. 164:5215. (Activ)
RRID
AB_2563101 (BioLegend Cat. No. 144902)

Antigen Details

Structure
Type I membrane protein belonging to Ig superfamily
Distribution
Myeloid cells, activated NK cells
Function
Inhibitory activity mediated by ITIM motif
Interaction
SHP-1 and SHP-2
Ligand/Receptor
Integrin αvβ3, collagen
Cell Type
NK cells, Dendritic cells
Biology Area
Immunology, Innate Immunity
Molecular Family
CD Molecules
Antigen References

1. Castells, MC, et al. 1994. J. Biol. Chem. 269:8393.
2. Katz HR, et al. 1996. P. Natl. Acad. Sci. USA 93:10809.
3. Kuroiwa A, et al. 1998. J. Biol. Chem. 273:1070.
4. Wang LL, et al. 2000. J. Immunol. 164:5215.
5. Jiang L, et al. 2009. Eur. J. Immunol. 39:1167.

Gene ID
14728 View all products for this Gene ID
UniProt
View information about CD85k on UniProt.org

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