FITC anti-mouse/human GL7 Antigen (T and B cell Ac
- 产品名称：
- FITC anti-mouse/human GL7 Antigen (T and B cell Ac
- 产品类别：
- 抗体
- 产品编号：
- 144603
- 产品应用：
- 144603
- Verified Reactivity
- Mouse, Human
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- LPS activated DBA/J mouse B cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
- Application Notes
The GL7 antibody does not block the binding of CD22 with sulfated a2-6-sialyl-LacNAc.
Cross-reactivity to ferret has been reported by a collaborator, but not verified in house.
- Application References
(PubMed link indicates BioLegend citation) -
- Laszlo G, et al. 1993. J. Immunol. 150:5252. (FC, IP)
- Hartgring SA, et al. 2012. Arthritis Res. Ther. 14:R137. (FC)
- Taylor JJ, et al. 2012. J. Exp. Med. 209:597. (FC, IHC)
- Balogh A, et al. 2010. Immunol. Lett. 130:89. (IHC)
- Kimura N, et al. 2007. J. Biol. Chem. 282:32200. (ELISA, FC)
- Product Citations
-
- Tan J, et al. 2021. iScience. 24(8):102835. PubMed
- Delvecchio FR, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:1543. PubMed
- Pack AD, et al. 2021. Cell Reports. 36(8):109586. PubMed
- Chen J et al. 2018. Cell reports. 25(12):3393-3404 . PubMed
- Tam H, et al. 2016. Proc Natl Acad Sci U S A. 113: E6639 - E6648. PubMed
- Yang D, et al. 2020. Nat Commun. 2.411111111. PubMed
- Bartleson JM, et al. 2020. Nat Immunol. 1384:21. PubMed
- Pérez‐Mazliah D et al. 2017. EBioMedicine. 24:216-230 . PubMed
- Biram A, et al. 2020. Cell Rep. 30:1910. PubMed
- Parthasarathy R, et al. 2021. Front Immunol. 12:758407. PubMed
- Super M, et al. 2021. Nat Biomed Eng. Online ahead of print. PubMed
- Wong R, et al. 2020. Immunity. 53(5):1078-1094.e7. PubMed
- Duan L, et al. 2021. Immunity. 54:2256. PubMed
- Volberding PJ, et al. 2021. Cell Reports. 35(8):109160. PubMed
- Crouse B, et al. 2020. NPJ Vaccines. 0.277083333. PubMed
- Beloor J et al. 2018. Cell host & microbe. 23(4):549-556 . PubMed
- Frost JN, et al. 2021. Med (N Y). 2:164. PubMed
- Guo C, et al. 2021. Cell Rep Med. 2:100448. PubMed
- Shiozawa S, et al. 2022. iScience. 25:103537. PubMed
- Zhang Y, et al. 2022. Vaccines (Basel). 10:. PubMed
- Stephens WZ, et al. 2021. Cell Rep. 37:109916. PubMed
- Zhang YN, et al. 2021. Sci Adv. 7:eabj3107. PubMed
- Xia Y, et al. 2018. Cell. 175:1059. PubMed
- Andersen TK, et al. 2019. NPJ Vaccines. 4:9. PubMed
- Yang C, et al. 2020. Cell Host Microbe. 467:27. PubMed
- Sisteré–Oró M, et al. 2020. Vet Res. 51:57:00. PubMed
- Zhong C, et al. 2021. J Virol. 95:e0092521. PubMed
- Voigt A, et al. 2016. Sci Rep. 6:38717. PubMed
- Matsushita N, et al. 2016. Sci Rep. 6:31266. PubMed
- Cooley L, et al. 2016. Sci Rep. 6: 25840. PubMed
- Platteel ACM, et al. 2018. Front Immunol. 1.544444444. PubMed
- Adachi Y, et al. 2015. J Exp Med. 212: 1709-1723. PubMed
- Chen Z, et al. 2020. J Immunol. 204:335. PubMed
- Robles-Valero J, et al. 2021. EMBO J. 40:e108125. PubMed
- Nasrallah R, et al. 2020. Nature. 583:447. PubMed
- BJ L, et al. 2017. J Exp Med . 10.1084/jem.20161461. PubMed
- Stienne C, et al. 2022. Cell Rep. 38:110553. PubMed
- RRID
- AB_2561696 (BioLegend Cat. No. 144603) AB_2561697 (BioLegend Cat. No. 144604)
- Structure
- 35 kD
- Distribution
-
Germinal center B cells, activated B and T cells
- Function
- Upregulated on activated B cells via in situ repression of CMP-Neu5Ac-hydroxylase
- Ligand/Receptor
- Neu5Ac-recognizing lectins
- Cell Type
- B cells, T cells
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules
- Antigen References
-
1. Laszlo G, et al. 1993. J. Immunol. 150:5252.
2. Hathcock KS, et al. 1995. J. Immunol. 155:4575.
3. Cervenak K, et al. 2001. Immunol. Lett. 78:89.
- Gene ID
- NA
- UniProt
- View information about GL7 on UniProt.org
