PE anti-mouse TCR Vδ4 Antibody
- 产品名称：
- PE anti-mouse TCR Vδ4 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 134905
- 产品应用：
- 134905
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Armenian Hamster
- Immunogen
- G57BL/6 mouse intestinal intra-epithelial lymphocytes
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application References
(PubMed link indicates BioLegend citation) -
- Lefrancois L, et al. 1990. Cell. 66:33
- Sperling AI, et al. 1992. J. Immunol. 149(10):3200
- Pereira P, et al. 1997. Proc. Natl. Acad. Sci. USA. 94:5761
- Product Citations
-
- Cibrián D, et al. 2020. J Allergy Clin Immunol. 145:199. PubMed
- Marco Barros R, et al. 2016. Cell. 167: 203-218. PubMed
- Kim SM, et al. 2019. FASEB J. 33:13386. PubMed
- Jandke A, et al. 2020. Nat Commun. 3.075694444. PubMed
- Lai NY, et al. 2020. Cell. 180:33:00. PubMed
- RRID
- AB_1877234 (BioLegend Cat. No. 134905)
- Structure
- Form heterodimer with TCR gamma chain, associate with CD3 complex.
- Distribution
- Expressed on Vδ4 T-cell receptor (TCR) bearing T cells, which are predominant γ/δ T cells in intestinal epithelium.
- Function
- Involved in immunological surveillance of epithelia separating the external environment from internal milieu.
- Ligand/Receptor
- Antigen peptide bound to MHC molecule
- Cell Type
- T cells
- Biology Area
- Immunology, Adaptive Immunity
- Molecular Family
- TCRs
- Antigen References
-
1. Reardon C et al. 1990. J. Exp. Med. 172:1263
2. Goodman T et al. 1989. J. Exp. Med. 170:1569
- Gene ID
- 110066 View all products for this Gene ID
- UniProt
- View information about TCR V delta 4 on UniProt.org
