Ultra-LEAF™ Purified anti-human CD85j (ILT2)
- 产品名称：
- Ultra-LEAF™ Purified anti-human CD85j (ILT2)
- 产品类别：
- 抗体
- 产品编号：
- 333721
- 产品应用：
- 333721
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- 0.2 ?m filtered in phosphate-buffered solution, pH 7.2, containing no preservative. Endotoxin level is <0.01 EU/?g of the protein (<0.001 ng/?g of the protein) as determined by the LAL test.
- Preparation
- The Ultra-LEAF? (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
- Concentration
- The antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. Older lots may have also been bottled at 1 mg/mL. To obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF? solution contains no preservative; handle under aseptic conditions.
- Application
-
FC - Quality tested
FA - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Additional reported application: Block HLA-G induced TGF-?1 production.
- Application References
(PubMed link indicates BioLegend citation) -
- Pulford K, et al. 1991. Clin. Exp. Immunol. 85:429
- Mclntire RH, et al. 2004. J. Leukoc. Biol. 76:1220
- Product Citations
-
- Zheng G, et al. 2021. Signal Transduct Target Ther. 6:236. PubMed
- RRID
- AB_2814223 (BioLegend Cat. No. 333721) AB_2814224 (BioLegend Cat. No. 333722)
- Structure
- ILT/LIR family, Ig superfamily, 110 kD
- Distribution
-
B cells, plasma cells, dendritic cells, monocytes, subsets of NK and T cells.
- Function
- Inhibitory receptor for MHC class I
- Ligand/Receptor
- HLA-A, -B, some HLA-C and G molecules, human cytomegalovirus UL18 protein
- Cell Type
- B cells, Dendritic cells, Monocytes, NK cells, Plasma cells, T cells
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Zola H, et al. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers Wiley-Liss A John Wiley & Sons Inc, Publication
2. Kirwan SE and Burshtyn DN. 2005. J. Immunol. 175:5006
- Gene ID
- 10859 View all products for this Gene ID
- UniProt
- View information about CD85j on UniProt.org
