PE anti-human CD163 Antibody
- 产品名称：
- PE anti-human CD163 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 333605
- 产品应用：
- 333605
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1176 |
1 |
- Verified Reactivity
- Human, Cynomolgus, Rhesus
- Reported Reactivity
- African Green
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Clone GHI/61 binds to domain 7 of CD163. Additional reported applications (for the relevant formats) include: immunocytochemical staining, immunoprecipitation,?western blot1, and spatial biology (IBEX)6,7.
- Application References
(PubMed link indicates BioLegend citation) -
- Pulford K,?et al.?1992.?Immunology?75:588. (ICC, IP, WB)
- Law SK,?et al.?1993.?Eur. J. Immunol.?23:2320.
- Madsen M,?et al.?2004.?J. Biol. Chem.?279:51561.
- Kim WK,?et al.?2006.?Am. J. Pathol.?168:822. (FC)
- Buttari B,?et al.?2011.?Atherosclerosis.?215:316.?PubMed
- Radtke AJ,?et al. 2020.?Proc Natl Acad Sci USA. 117:33455-33465. (SB)?PubMed
- Radtke AJ,?et al. 2022.?Nat Protoc. 17:378-401. (SB)?PubMed
- Product Citations
-
- Friebel E, et al. 2020. Cell. 181(7):1626-1642.e20. PubMed
- Lathrop S, et al. 2015. Infect Immun . 83: 2661 - 2671. PubMed
- Hashimoto M, et al. 2015. J Immunol. 95: 4341 - 4350. PubMed
- Sakamoto S, et al. 2020. OncoImmunology. 8(12):e1671760.. PubMed
- Wu T, et al. 2022. Cell Death Dis. 13:624. PubMed
- He C, et al. 2021. Oncoimmunology. 1897295:10. PubMed
- Ma L, et al. 2021. Clinical Cancer Research. 27(6):1778-1791. PubMed
- Meng Y,et al. 2017. Cell Death Dis. . 10.1038/cddis.2017.505. PubMed
- Iwabuchi R, et al. 2021. Frontiers in Immunology. 12:643040. PubMed
- Karagianni AE, et al. 2021. Sci Rep. 11:14292. PubMed
- Souriant S, et al. 2019. Cell Rep. 26:3586. PubMed
- Huang Y, et al. 2022. Front Immunol. 13:993788. PubMed
- Zangeneh Z, et al. 2022. Iran J Basic Med Sci. 25:474. PubMed
- Mendoza-Cabrera MI, et al. 2019. Innate Immun. :1753425919864658. PubMed
- Anderson AE, et al. 2022. NPJ Regen Med. 7:6. PubMed
- Wendisch D, et al. 2021. Cell. 184:6243. PubMed
- Genoula M, et al. 2018. Front Immunol. 9:459. PubMed
- Burwitz B, et al. 2014. J Leukoc Biol. 96:491. PubMed
- Hashimoto M, et al. 2014. Cell Death Dis. 5:1267. PubMed
- Chakraborty M, et al. 2021. Cell Reports. 34(2):108609. PubMed
- Saraiva DP, et al. 2018. Front Immunol. 2.184027778. PubMed
- Ball M, et al. 2016. PLoS One. 11: 0149600. PubMed
- Liu Y, et al. 2022. Clin Transl Med. 12:e654. PubMed
- Nakajima S, et al. 2021. Mol Cancer Res. 19:1085. PubMed
- Wu Q, et al. 2022. Cancer Immunol Res. 10:182. PubMed
- Stempin CC, et al. 2021. Cancers (Basel). 13:. PubMed
- Osman A, et al. 2014. J Immunol. 192:5083. PubMed
- Luvanda MK, et al. 2021. J Fungi (Basel). 7:. PubMed
- Martins AJ, et al. 2017. Cell Systems. 4(4):379-392.e12. PubMed
- Wang R, et al. 2019. EBioMedicine. 40:118. PubMed
- RRID
- AB_1134005 (BioLegend Cat. No. 333605) AB_1134002 (BioLegend Cat. No. 333606)
- Structure
- 134 kD (non-reduced)/155 kD (reduced) glycoprotein, scavenger receptor superfamily
- Distribution
-
Monocytes, macrophages, Kuffer cells, subset of dendritic cells, subset of hematopoietic stem/progenitor cells
- Function
- Clearance of haptoglobin-hemoglobin complex, regulation of cytokine production by macrophages
- Ligand/Receptor
- Haptoglobin-hemoglobin complex, TWEAK
- Cell Type
- Dendritic cells, Hematopoietic stem and progenitors, Macrophages, Monocytes
- Biology Area
- Cell Biology, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
- Molecular Family
- CD Molecules
- Antigen References
-
1. Roth J, et al. 1994 Transolantation. 57:127
2. Van den Heuvel MM, et al.1999 J. Leukoc. Biol. 66:858
3. Sulahian TH, et al. 2000 Cytokines 12:1312
4. Fabriek BO, et al. 2007 J. Neuroimmunol. 187:179
- Gene ID
- 9332 View all products for this Gene ID
- UniProt
- View information about CD163 on UniProt.org
