APC anti-human CD163 Antibody
- 产品名称：
- APC anti-human CD163 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 333609
- 产品应用：
- 333609
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1704 |
1 |
- Verified Reactivity
- Human, Cynomolgus, Rhesus
- Reported Reactivity
- African Green
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Red Laser (633 nm)
- Application Notes
Clone GHI/61 binds to domain 7 of CD163. Additional reported applications (for the relevant formats) include: immunocytochemical staining, immunoprecipitation,?western blot1, and spatial biology (IBEX)6,7.
- Application References
(PubMed link indicates BioLegend citation) -
- Pulford K,?et al.?1992.?Immunology?75:588. (ICC, IP, WB)
- Law SK,?et al.?1993.?Eur. J. Immunol.?23:2320.
- Madsen M,?et al.?2004.?J. Biol. Chem.?279:51561.
- Kim WK,?et al.?2006.?Am. J. Pathol.?168:822. (FC)
- Buttari B,?et al.?2011.?Atherosclerosis.?215:316.?PubMed
- Radtke AJ,?et al. 2020.?Proc Natl Acad Sci USA. 117:33455-33465. (SB)?PubMed
- Radtke AJ,?et al. 2022.?Nat Protoc. 17:378-401. (SB)?PubMed
- Product Citations
-
- Zizzo G, et al. 2012. J Immunol. 189:3508. PubMed
- Loegl J, et al. 2016. Reproduction. 152: 447 - 455. PubMed
- Hsu SPC, et al. 2020. J Neurooncol. 146:417. PubMed
- Conforti A, et al. 2021. PLoS One. 16:e0259894. PubMed
- Weisberg SP, et al. 2020. Cell Reports. 29(12):3916-3932.e5.. PubMed
- Naftali-Shani N, et al. 2013. J Am Heart Assoc. 2:253. PubMed
- Cassetta L et al. 2019. Cancer Cell. 35(4):588-602 . PubMed
- Kim SE, et al. 2019. PLoS One. 14:e0223590. PubMed
- Norton S, et al. 2016. Clin Transl Immunology. 5: e76. PubMed
- Sefik E, et al. 2021. Nat Biotechnol. . PubMed
- Arlt A, et al. 2020. Mol Oncol. 14:571. PubMed
- Madsen NH, et al. 2021. Pathogens. 10:. PubMed
- Cecotto L, et al. 2022. iScience. 25:105211. PubMed
- Vogelpoel L, et al. 2014. Nat Commun. 5:5444. PubMed
- Guo L, et al. 2014. J Virol. 88:10448. PubMed
- Mathewson ND, et al. 2021. Cell. 184(5):1281-1298.e26. PubMed
- Chen X, et al. 2022. Cell Commun Signal. 20:92. PubMed
- Tang Z, et al. 2013. Endocrinology. 154:471. PubMed
- Li F, et al. 2022. iScience. 25:105147. PubMed
- RRID
- AB_2291272 (BioLegend Cat. No. 333609) AB_2074533 (BioLegend Cat. No. 333610)
- Structure
- 134 kD (non-reduced)/155 kD (reduced) glycoprotein, scavenger receptor superfamily
- Distribution
-
Monocytes, macrophages, Kuffer cells, subset of dendritic cells, subset of hematopoietic stem/progenitor cells
- Function
- Clearance of haptoglobin-hemoglobin complex, regulation of cytokine production by macrophages
- Ligand/Receptor
- Haptoglobin-hemoglobin complex, TWEAK
- Cell Type
- Dendritic cells, Hematopoietic stem and progenitors, Macrophages, Monocytes
- Biology Area
- Cell Biology, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
- Molecular Family
- CD Molecules
- Antigen References
-
1. Roth J, et al. 1994 Transolantation. 57:127
2. Van den Heuvel MM, et al.1999 J. Leukoc. Biol. 66:858
3. Sulahian TH, et al. 2000 Cytokines 12:1312
4. Fabriek BO, et al. 2007 J. Neuroimmunol. 187:179
- Gene ID
- 9332 View all products for this Gene ID
- UniProt
- View information about CD163 on UniProt.org
