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首页 > 抗体蛋白 > 抗体
APC anti-mouse CD326 (Ep-CAM) Antibody
产品名称：
APC anti-mouse CD326 (Ep-CAM) Antibody
产品类别：
抗体
产品编号：
118213
产品应用：
118213
[价格]
规格 价格 库存
25µg ￥ 1224 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
TE-71 thymic epithelial cell line
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 ?g per 106 cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application Notes

Additional reported applications for clone G8.8 (for the relevant formats) include: immunohistochemistry of?frozen sections: acetone fixed1, with or without OCT embedding2,4, and spatial biology (IBEX)13,14.

Application References

(PubMed link indicates BioLegend citation)
  1. Farr A, et al. 1991. J. Histochem. Cytochem. 39:645. (FC, IHC)
  2. Dooley J, et al. 2005. J. Immunol. 175:4331. (FC, IHC)
  3. Hinterberger M, et. al. 2010. Nat. Immunol. 11:512. (FC) PubMed
  4. Gracz AD, et al. 2010. Am J. Physiol Gastrointest Liver Physiol. 298:590. (IHC) PubMed
  5. Nudel I, et al. 2011. J. Immunol. 186:891. PubMed
  6. Morimoto H, et al. 2012. Biol Reprod. 86:148. PubMed
  7. Ishii K, et al. 2012. Development. 139:1734. PubMed
  8. Takehashi M, et al. 2012. Biol Reprod. 86:178. PubMed
  9. Murakami R, et al. 2013. PLoS One. 8:73270. PubMed
  10. Taguchi K, et al. 2014. Mol Cell Biol. 34:900. PubMed
  11. Hirokawa Y, et al. 2014. Am J Physiol Gastrointerest Liver Physiol. 306:547. PubMed
  12. Ding X, et al. 2015. Cancer Res. 75:330. PubMed
  13. Radtke?AJ,?et al.?2020.?Proc Natl Acad Sci U S A.?117:33455-65. (SB)?PubMed
  14. Radtke?AJ,?et al.?2022.?Nat Protoc.?17:378-401. (SB)?PubMed
Product Citations
  1. Serra-Hassoun M, et al. 2014. J Immunol. 193:1504. PubMed
  2. Elkon R, et al. 2015. Nat Commun. 6: 8549. PubMed
  3. Bowling S, et al. 2020. Cell. 181(6):1410-1422.e27. PubMed
  4. Sun L, et al. 2021. Cancer Cell. :. PubMed
  5. Chen Q, et al. 2020. Cell Reports. 31(13):107828. PubMed
  6. Garo LP, et al. 2021. Nat Commun. 12:2419. PubMed
  7. Hohmann MS, et al. 2021. JCI Insight. 6:. PubMed
  8. Zhu Y, et al. 2022. Nat Commun. 13:4282. PubMed
  9. Boyd DF, et al. 2020. Nature. 587:466. PubMed
  10. Mevel R, et al. 2020. eLife. 9:00. PubMed
  11. Lv X, et al. 2022. Acta Pharm Sin B. 12:735. PubMed
  12. Buerger S, et al. 2015. J Immunol. 195: 4106 - 4116. PubMed
  13. Malhotra D, et al. 2016. Nat Immunol. 17:187-195. PubMed
  14. Cheung P, et al. 2020. Cell Stem Cell. 27(4):590-604.e9. PubMed
  15. Komban RJ, et al. 2019. Nat Commun. 10:2423. PubMed
  16. Kato T, et al. 2019. Front Immunol. 10:2021. PubMed
  17. Shultz L, et al. 2010. Proc Natl Acad Sci U S A. 107:13022. PubMed
  18. Ford MJ, et al. 2021. Cell Rep. 36:109677. PubMed
  19. Paris AJ, et al. 2020. Nat Cell Biol. 1.747916667. PubMed
  20. Phung HT, et al. 2020. Immunohorizons. 0.25625. PubMed
  21. Nishina T, et al. 2021. Nat Commun. 12:2281. PubMed
  22. Chua CW, et al. 2018. Elife. 7. PubMed
  23. Finn J et al. 2019. Cell reports. 26(11):2942-2954 . PubMed
  24. Semba T, et al. 2020. Cancers (Basel). 12:. PubMed
  25. Ludwik KA, et al. 2021. STAR Protocols. 2(1):100270. PubMed
  26. Santos CP et al. 2019. Nat Commun. 10(1):4407 . PubMed
  27. Willobee BA, et al. 2021. Mol Cancer Ther. 20:1246. PubMed
  28. Wang Y, et al. 2014. PLoS One. 9:113127. PubMed
  29. Katara GK, et al. 2020. Mol Oncol. 0.729861111. PubMed
  30. Malik A et al. 2018. Immunity. 49(3):515-530 . PubMed
  31. Goldfarb Y, et al. 2021. J Exp Med. 218:. PubMed
  32. Liu S, et al. 2020. Cell Host & Microbe. 26(6):779-794.e8.. PubMed
  33. Rudnick JA, et al. 2021. Genes Dev. 35:963. PubMed
  34. Lü?nd F, et al. 2022. STAR Protoc. 3:101438. PubMed
  35. Wu H, et al. 2021. Cell Death Discov. 7:225. PubMed
  36. Jiang M, et al. 2021. Developmental Cell. 56(11):1646-1660.e5. PubMed
  37. Barone F, et al. 2015. Proc Natl Acad Sci U S A. 112: 11024-11029. PubMed
  38. Bar C, et al. 2020. Cell Reports. 28(1):257-266.e5.. PubMed
  39. Xi‐Zhi J Guo et al. 2018. Immunity. 49(3):531-544 . PubMed
  40. Sateriale A, et al. 2020. Cell Host & Microbe. 26(1):135-146.e5.. PubMed
  41. Tuong ZK, et al. 2021. iScience. 24:103326. PubMed
  42. Ionkina AA, et al. 2021. Breast Cancer Res. 23:93. PubMed
  43. Zhang Z, et al. 2021. Exp Dermatol. 30:102. PubMed
  44. Hertzano R, et al. 2020. Laryngoscope. . PubMed
  45. Li J, et al. 2020. Development. . PubMed
  46. Cerretelli G, et al. 2021. J Pathol. 255:464. PubMed
  47. Tang Z, et al. 2021. Stem Cell Res Ther. 12:397. PubMed
  48. Christin JR, et al. 2020. Cell Reports. 31(10):107742. PubMed
  49. McGinty JW, et al. 2020. Immunity. 52(3):528-541. PubMed
  50. Zhang Y, et al. 2021. Commun Biol. 344:4. PubMed
  51. Li MY, et al. 2021. Developmental Cell. :. PubMed
  52. Caporarello N, et al. 2020. Aging Cell. 19:e13196. PubMed
  53. Pepe‐Mooney BJ et al. 2019. Cell Stem Cell. 25(1):23-38 . PubMed
  54. Smith NR, et al. 2018. Cell Mol Gastroenterol Hepatol. 6:79. PubMed
  55. Gerdes P, et al. 2022. Nat Commun. 13:7470. PubMed
  56. Ualiyeva S, et al. 2021. Bio Protoc. 11:e4163. PubMed
  57. Ognjenovic NB, et al. 2020. Dev Cell. 55:544. PubMed
  58. King J, et al. 2012. Am J Physiol Gastrointest Liver Physiol. 303:443. PubMed
  59. Yoshida H, et al. 2019. Cell. 176:897. PubMed
  60. Baptista M, et al. 2016. Nat Commun. 7:12175. PubMed
  61. Castillo–Azofeifa D, et al. 2019. EMBO J. 38:e99984. PubMed
  62. Tippimanchai DD, et al. 2018. Oncoimmunology. 7:e1438105. PubMed
  63. Chetty A, et al. 2021. Cell Host Microbe. 29:579. PubMed
  64. Casey O, et al. 2012. PLoS One. 7:e41668. PubMed
  65. Tanimizu N, et al. 2014. J Biol Chem. 289:7859. PubMed
  66. Kasuga A, et al. 2020. Cancer Sci. . PubMed
  67. Gross KM, et al. 2019. Cell Rep. 28:394. PubMed
  68. Lai NY, et al. 2020. Cell. 180:33:00. PubMed
  69. Caporarello N, et al. 2022. Nat Commun. 13:4170. PubMed
  70. Chen Z, et al. 2020. Immunity. 54(1):151-163.e6. PubMed
  71. Tripathi D, et al. 2016. Nat Commun. 7:13896. PubMed
  72. Han H, et al. 2020. Cancer Cell. 36(5):483-497.e15.. PubMed
  73. Jadhav U, et al. 2019. Mol Cell. 74:542. PubMed
  74. Renz BW, et al. 2018. Cancer Cell. 33:75. PubMed
  75. Cohen I et al. 2018. Cell stem cell. 22(5):726-739 . PubMed
  76. Lehmann M, et al. 2020. Cell Signal. 70:109588. PubMed
RRID
AB_1134105 (BioLegend Cat. No. 118213) AB_1134102 (BioLegend Cat. No. 118214)

Antigen Details

Structure
40 kD single-pass type 1 glycoprotein. 293 amino acids, with a 21 aa signal peptide, a 246 aa extracellular domain, a 21 aa transmembrane domain, and a 26 aa cytoplasmic domain. The extracellular domain contains two epidermal growth factor-like repeats.
Distribution

Expressed on majority of epithelial cell membranes with the exception of adult squamous cells of the skin and a few specific epithelial cell types.

Function
Mediates calcium-independent homophilic cell-cell adhesion.
Interaction
CD326 displays hemophilic binding.
Ligand/Receptor
CD305 (LAIR-1), CD306 (LAIR-2), and Ep-CAM.
Cell Type
Embryonic Stem Cells, Epithelial cells
Biology Area
Immunology, Stem Cells
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Borkowski TA, et al. 1996. Eur. J. Immunol. 26:110.
2. Bergsagel PL, et al. 1992. J. Immunol. 148:590.

Gene ID
17075 View all products for this Gene ID
UniProt
View information about CD326 on UniProt.org

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