Purified anti-human CD66b Antibody
- 产品名称：
- Purified anti-human CD66b Antibody
- 产品类别：
- 抗体
- 产品编号：
- 305102
- 产品应用：
- 305102
- Verified Reactivity
- Human
- Reported Reactivity
- Chimpanzee
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
IHC-P - Verified
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. For immunohistochemical staining on formalin-fixed paraffin-embedded tissue sections, the suggested use of this reagent is 5.0 - 10 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen,?formalin-fixed paraffin-embedded tissue sections, and spatial biology (IBEX)5,6.
- Application References
(PubMed link indicates BioLegend citation) -
- Schlossman S, et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York.
- Kishimoto T, et al. Eds. 1997. Leucocyte Typing VI. Garland Publishing Inc. London.
- Norling LV, et al. 2012. Arterioscler Thromb Vasc Biol. 32:1970. PubMed
- Meinke P, et al. 2015. Neuroimmunol Discord. 25:127. PubMed
- Radtke AJ,?et al. 2020.?Proc Natl Acad Sci USA. 117:33455-33465. (SB)?PubMed
- Radtke AJ,?et al. 2022.?Nat Protoc. 17:378-401. (SB)?PubMed
- Product Citations
-
- Miyamoto DT, et al. 2018. Cancer Discov. 0.533333333. PubMed
- Weinhage T, et al. 2020. J Immunol. 205:56. PubMed
- Taft J, et al. 2021. Cell. 184(17):4447-4463.e20. PubMed
- Stras SF, et al. 2020. Developmental Cell. 51(3):357-373.e5.. PubMed
- Arnold IC, et al. 2018. J Exp Med. 215:2055. PubMed
- Arunachalam PS, et al. 2021. Nature. 596:410. PubMed
- Schimek V, et al. 2022. Cell Death Dis. 13:113. PubMed
- Cao Q, et al. 2018. Am J Physiol Renal Physiol. 314:F561. PubMed
- Mann ER, et al. 2020. Sci Immunol. :5. PubMed
- Xu G, et al. 2021. Cell Res. 31:1230. PubMed
- Xu L, et al. 2022. Nat Commun. 13:4892. PubMed
- Meinke P, et al. 2015. Neuromuscul Disord. 25:127. PubMed
- Martin JC, et al. 2020. Cell. 178(6):1493-1508.e20.. PubMed
- Li H, et al. 2020. Front Immunol. 11:1777. PubMed
- Eldredge LC, et al. 2019. Am J Physiol Lung Cell Mol Physiol. 317:L49. PubMed
- Governa V, et al. 2017. Clin Cancer Res. 23:3847. PubMed
- Aymonnier K, et al. 2022. Blood Adv. . PubMed
- Ehinger E, et al. 2021. Cardiovasc Res. 117:1166. PubMed
- Bartsch YC, et al. 2021. MBio. 12:. PubMed
- Pelka K, et al. 2021. Cell. 184(18):4734-4752.e20. PubMed
- Norling L, et al. 2012. Arterioscler Thromb Vasc Biol. 32:1970. PubMed
- Fischinger S, et al. 2020. JCI Insight. 5:00. PubMed
- De Maeyer RPH, et al. 2020. Nat Immunol. 21:615. PubMed
- Martin A, et al. 2018. Oncotarget. 9:28364. PubMed
- Yu KK, et al. 2021. JCI Insight. 6:. PubMed
- Tiberti S, et al. 2022. Nat Commun. 13:6752. PubMed
- Oh J, et al. 2021. Clin Cancer Res. 27:4781. PubMed
- Leylek R, et al. 2020. Cell Rep. 32:108180. PubMed
- Lavin Y et al. 2017. Cell. 169(4):750-765 . PubMed
- Debien V, et al. 2021. Cancers (Basel). 13:. PubMed
- RRID
- AB_314494 (BioLegend Cat. No. 305102)
- Structure
- Ig superfamily, CEA antigen group, GPI-linked glycoprotein, 95-100 kD
- Distribution
-
Granulocytes
- Function
- Cell adhesion, neutrophil activation
- Ligand/Receptor
- CD66c
- Cell Type
- Granulocytes, Neutrophils
- Biology Area
- Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Kuijpers T, et al. 1993. J. Immunol. 151:4934.
2. Kuroki M, et al. 1992. J. Leuk. Biol. 52:551.
- Gene ID
- 1088 View all products for this Gene ID
- UniProt
- View information about CD66b on UniProt.org
