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PE anti-human CD32 Antibody
产品名称:
PE anti-human CD32 Antibody
产品类别:
抗体
产品编号:
303205
产品应用:
303205
[价格]
规格 价格 库存
25tests ¥ 1404 1

产品详情

Product Details

Verified Reactivity
Human
Reported Reactivity
African Green, Baboon, Cynomolgus, Rhesus
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported applications (for the relevant formats) include: immunohistochemical staining3 of acetone-fixed frozen tissue sections.?

Clone FUN-2 recognizes both CD32A and CD32B.

Application References

(PubMed link indicates BioLegend citation)
  1. Kishimoto T, et al. 1997. Leucocyte Typing VI Garland Press. London.
  2. Lerino F, et al. 1993. J. Immunol. 150:1794.
  3. Personal communication.
  4. van Tits L, et al. 2005. Arterioscler Thromb Vasc Biol. 25:717.PubMed
  5. Smeltz RB. 2007. J. Immunol. 178:4786.
  6. Satta N, et al. 2011. Blood. 117:5223. PubMed.
Product Citations
  1. Li H, et al. 2016. J Immunol. 196: 4064 - 4074. PubMed
  2. Cines DB, et al. 2020. Blood. 135:2085. PubMed
  3. Abdel–Mohsen M, et al. 2018. Sci Transl Med. 10:eaar6759. PubMed
  4. Asokan M, et al. 2020. Proc Natl Acad Sci U S A. 117:18754. PubMed
  5. Zhang X, et al. 2016. J Immunol. 196: 1165 - 1176. PubMed
  6. Morris AB, et al. 2020. Immunity. 52(1):136-150.e6.. PubMed
  7. Wu X, et al. 2018. J Immunol Methods. 455:71. PubMed
  8. Inui M, et al. 2015. Int Immunol. 27: 345 - 355. PubMed
  9. Wu X, et al. 2020. Front Immunol. 1.922222222. PubMed
  10. Gage BK, et al. 2020. Cell Stem Cell. 27(2):254-269.e9. PubMed
RRID
AB_314337 (BioLegend Cat. No. 303205) AB_314338 (BioLegend Cat. No. 303206)

Antigen Details

Structure
Ig superfamily, polymorphic transmembrane glycoprotein, 40 kD
Distribution

Monocytes, granulocytes, B cells, platelets

Function
Endocytosis, cytotoxicity, platelet aggregation, B cell function
Ligand/Receptor
Aggregated IgG, immune complex
Cell Type
B cells, Dendritic cells, Granulocytes, Monocytes, Platelets
Biology Area
Immunology, Innate Immunity
Molecular Family
CD Molecules, Fc Receptors
Antigen References

1. Stuart S, et al. 1989. EMBO J. 8:3657.
2. Huang Y, et al. 1999. Scand. J. Immunol. 49:177.
3. Hisaka H, et al. 1999. Pathobiology 67:92.

Gene ID
2212 View all products for this Gene ID
UniProt
View information about CD32 on UniProt.org

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