Brilliant Violet 421™ anti-human CD69 Antibo
- 产品名称：
- Brilliant Violet 421™ anti-human CD69 Antibo
- 产品类别：
- 抗体
- 产品编号：
- 310929
- 产品应用：
- 310929
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 2112 |
1 |
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon, Chimpanzee, Cynomolgus, Pigtailed Macaque, Rhesus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 421? under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
Brilliant Violet 421? excites at 405 nm and emits at 421 nm. The standard bandpass filter 450/50 nm is recommended for detection. Brilliant Violet 421? is a trademark of Sirigen Group Ltd.
Learn more about Brilliant Violet?.
This product is subject to proprietary rights of Sirigen Inc. and is made and sold under license from Sirigen Inc. The purchase of this product conveys to the buyer a non-transferable right to use the purchased product for research purposes only. This product may not be resold or incorporated in any manner into another product for resale. Any use for therapeutics or diagnostics is strictly prohibited. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents. - Excitation Laser
- Violet Laser (405 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections2, immunofluorescence microscopy3, and spatial biology (IBEX)8,9.
- Application References
(PubMed link indicates BioLegend citation) -
- Knapp WB, et al. 1989. Leucocyte Typing IV. Oxford University Press. New York.
- Sakkas LI, et al. 1998. Clin. and Diag. Lab. Immunol. 5:430. (IHC)
- Kim JR, et al. 2005. BMC Immunol. 6:3. (IF)
- Verjans GM, et al. 2007. P. Natl. Acad. Sci. USA 104:3496.
- Lu H, et al. 2009. Toxicol Sci. 112:363. (FC) PubMed
- Thakral D, et al. 2008. J. Immunol. 180:7431. (FC) PubMed
- Yoshino N, et al. 2000. Exp. Anim. (Tokyo) 49:97. (FC)
- Radtke AJ,?et al. 2020.?Proc Natl Acad Sci USA. 117:33455-33465. (SB)?PubMed
- Radtke AJ,?et al. 2022.?Nat Protoc. 17:378-401. (SB)?PubMed
- Product Citations
-
- Carpenter RS, et al. 2019. Sci Rep. 9:19105. PubMed
- Policicchio B, et al. 2016. PLoS Pathog. 12: 1005879. PubMed
- Kagoya Y, et al. 2018. Nat Commun. 9:1915. PubMed
- Caduff N, et al. 2021. Cell Reports. 35(5):109056. PubMed
- Nguyen THO, et al. 2021. Immunity. 54:1066. PubMed
- Carnevale J, et al. 2022. Nature. 609:174. PubMed
- Prete G, et al. 2014. Antimicrob Agents Chemother. 58:6790. PubMed
- Cooper GE, et al. 2018. Front Immunol. 9:1671. PubMed
- Buggert M, et al. 2020. Cell. 183(7):1946-1961.e15. PubMed
- Bourges C, et al. 2020. EMBO Mol Med. 12:e12112. PubMed
- Ge C, et al. 2020. Cell Reports. 29(13):4236-4244.e3.. PubMed
- Dunn JLM, et al. 2021. Mucosal Immunol. 14:1133. PubMed
- Dai Z, et al. 2022. Signal Transduct Target Ther. 7:85. PubMed
- Sagebiel AF, et al. 2019. Nat Commun. 10:975. PubMed
- NULL, et al. 2022. Cell. 185:916. PubMed
- Pi J, et al. 2022. J Nanobiotechnology. 20:36. PubMed
- Mathewson ND, et al. 2021. Cell. 184(5):1281-1298.e26. PubMed
- Dulberger CL et al. 2017. Immunity. 46(6):1018-1029 . PubMed
- Hara T, et al. 2021. Cancer Cell. 39(6):779-792.e11. PubMed
- Pettmann J, et al. 2021. eLife. 10:00. PubMed
- Lucic B, et al. 2019. Nat Commun. 10:4059. PubMed
- Garcia EG, et al. 2020. Leukemia. 35:679. PubMed
- Gruijs M, et al. 2021. Int J Mol Sci. 22:. PubMed
- RRID
- AB_10933255 (BioLegend Cat. No. 310929) AB_2561909 (BioLegend Cat. No. 310930)
- Structure
- C-type lectin, type II glycoprotein, 28/32 kD
- Distribution
-
Activated T cells, B cells, NK cells, granulocytes, thymocytes, platelets, Langerhans cells
- Function
- Lymphocyte, monocyte, and platelet activation, NK cell killing
- Cell Type
- B cells, Granulocytes, Langerhans cells, NK cells, Platelets, T cells, Thymocytes, Tregs
- Biology Area
- Costimulatory Molecules, Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Schlossman S, et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York.
2. Testi R, et al. 1994. Immunol. Today 15:479.
- Gene ID
- 969 View all products for this Gene ID
- UniProt
- View information about CD69 on UniProt.org
