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首页 > 抗体蛋白 > 抗体
APC anti-human CD69 Antibody
产品名称：
APC anti-human CD69 Antibody
产品类别：
抗体
产品编号：
310909
产品应用：
310909
[价格]
规格 价格 库存
25tests ￥ 864 1

产品详情

Product Details

Verified Reactivity
Human
Reported Reactivity
African Green, Baboon, Chimpanzee, Cynomolgus, Pigtailed Macaque, Rhesus
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser
Red Laser (633 nm)
Application Notes

Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections2, immunofluorescence microscopy3, and spatial biology (IBEX)8,9.

Application References

(PubMed link indicates BioLegend citation)
  1. Knapp WB, et al. 1989. Leucocyte Typing IV. Oxford University Press. New York.
  2. Sakkas LI, et al. 1998. Clin. and Diag. Lab. Immunol. 5:430. (IHC)
  3. Kim JR, et al. 2005. BMC Immunol. 6:3. (IF)
  4. Verjans GM, et al. 2007. P. Natl. Acad. Sci. USA 104:3496.
  5. Lu H, et al. 2009. Toxicol Sci. 112:363. (FC) PubMed
  6. Thakral D, et al. 2008. J. Immunol. 180:7431. (FC) PubMed
  7. Yoshino N, et al. 2000. Exp. Anim. (Tokyo) 49:97. (FC)
  8. Radtke AJ,?et al. 2020.?Proc Natl Acad Sci USA. 117:33455-33465. (SB)?PubMed
  9. Radtke AJ,?et al. 2022.?Nat Protoc. 17:378-401. (SB)?PubMed
Product Citations
  1. S?gaard O, et al. 2015. PLoS One. 11: 1005142. PubMed
  2. Couturier J, et al. 2016. Retroviology. 13:30. PubMed
  3. Rad S M AH, et al. 2020. PLoS One. 15:e0232915. PubMed
  4. Netsrithong R, et al. 2020. Stem Cell Research. 39:101487.. PubMed
  5. Zeng W, et al. 2017. Front Immunol. 0.806944444. PubMed
  6. Manukyan G, et al. 2020. Auto Immun Highlights. 11:5. PubMed
  7. Neidleman J, et al. 2020. Elife. 9:00. PubMed
  8. Bonnefoy F, et al. 2018. Front Immunol. 2.170833333. PubMed
  9. Xiao C, et al. 2022. iScience. 25:103934. PubMed
  10. Wu Y, et al. 2021. Nat Biomed Eng. 5:1336. PubMed
  11. Chen M, et al. 2021. Cancers (Basel). 13:. PubMed
  12. Gao Y, et al. 2021. Oncogenesis. 10:62. PubMed
  13. Seamon K, et al. 2020. Front Immunol. 11:396. PubMed
  14. Huang C, et al. 2020. Theranostics. 10:10498. PubMed
  15. Urbanska K, et al. 2015. Cancer Immunol Res. 3: 1130 - 1137. PubMed
  16. Paraiso HC, et al. 2018. J Neuroinflammation. 0.694444444. PubMed
  17. Beatson RE, et al. 2021. Cell Rep Med. 2:100473. PubMed
  18. Hill ZB, et al. 2018. Nat Chem Biol. 14:112. PubMed
  19. Turner AW, et al. 2020. ACS Infect Dis. 6:1719. PubMed
  20. Vanshylla K, et al. 2022. Cell Host Microbe. 30:69. PubMed
  21. Huang M, et al. 2021. BMC Infect Dis. 21:922. PubMed
  22. Ping Y, et al. 2020. Front Cell Dev Biol. 0.890972222. PubMed
  23. Qiu C, et al. 2022. Front Immunol. 12:764949. PubMed
  24. Luengo A, et al. 2020. Molecular Cell. 81(4):691-707.e6. PubMed
  25. Wu D, et al. 2020. Biomark Res. 8:3. PubMed
  26. Gudgeon N, et al. 2022. Cell Rep. 40:111193. PubMed
  27. Zhang J, et al. 2022. Nature. 609:369. PubMed
  28. Cai J, et al. 2021. eLife. 10:00. PubMed
  29. Arcangeli S, et al. 2022. J Clin Invest. 132:. PubMed
  30. Liu Y, et al. 2022. Biochem J. 479:385. PubMed
  31. Draganov DD, et al. 2019. J Transl Med. 17:100. PubMed
  32. Jeng MY, et al. 2018. J Exp Med. 215:51. PubMed
  33. Krishnan S, et al. 2021. Clin Exp Immunol. 203:458. PubMed
  34. Wei Z, et al. 2021. Nat Commun. 0.805555556. PubMed
  35. Pan Y, et al. 2018. Proc Natl Acad Sci U S A. 115:992. PubMed
  36. Cho JH, et al. 2021. Nat Commun. 12:792. PubMed
  37. Vinogradova EV, et al. 2020. Cell. 182(4):1009-1026.e29. PubMed
  38. Roybal KT et al. 2016. Cell. 167(2):419-432 . PubMed
  39. Huang Z, et al. 2020. Sci Adv. 6:eaay9209. PubMed
  40. Fiorillo E, et al. 2010. J Biol Chem. 285:26506. PubMed
  41. O'Donoghue GP, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  42. Georg P, et al. 2022. Cell. 185:493. PubMed
  43. Pahl JHW, et al. 2018. Cancer Immunol Res. 0.609027778. PubMed
  44. Zhu YP et al. 2018. Cell reports. 24(9):2329-2341 . PubMed
  45. Menges D, et al. 2022. Nat Commun. 13:4855. PubMed
  46. Wang Y, et al. 2021. Sci Adv. 7: . PubMed
  47. Santopaolo M, et al. 2021. Front Immunol. 609406:12. PubMed
  48. Lee YG, et al. 2019. Nat Commun. 10:2681. PubMed
  49. Li H, et al. 2020. Front Oncol. 1.477083333. PubMed
  50. Masuda N, et al. 2021. BMC Cancer. 21:1269. PubMed
  51. Wang Y, et al. 2021. Cell Reports. 36(6):109516. PubMed
  52. Dyson MR, et al. 2020. MAbs. 12:1829335. PubMed
  53. Warthan MD, et al. 2018. Biol Reprod. 98:309. PubMed
  54. Li Q, et al. 2022. J Biol Chem. :101753. PubMed
  55. Tiwarekar V, et al. 2018. J Virol. 92:17. PubMed
  56. Ickrath P, et al. 2018. Int J Mol Med. 42:1116. PubMed
  57. Xiao C, et al. 2021. STAR Protoc. 2:100789. PubMed
  58. Dijkman K, et al. 2021. Cell Reports Medicine. 2(1):100187. PubMed
  59. van Galen P, et al. 2019. Cell. 176:1265. PubMed
  60. Schmidts A, et al. 2020. J Immunother Cancer. 8:. PubMed
RRID
AB_314844 (BioLegend Cat. No. 310909) AB_314845 (BioLegend Cat. No. 310910)

Antigen Details

Structure
C-type lectin, type II glycoprotein, 28/32 kD
Distribution

Activated T cells, B cells, NK cells, granulocytes, thymocytes, platelets, Langerhans cells

Function
Lymphocyte, monocyte, and platelet activation, NK cell killing
Cell Type
B cells, Granulocytes, Langerhans cells, NK cells, Platelets, T cells, Thymocytes, Tregs
Biology Area
Costimulatory Molecules, Immunology
Molecular Family
CD Molecules
Antigen References

1. Schlossman S, et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York.
2. Testi R, et al. 1994. Immunol. Today 15:479.

Gene ID
969 View all products for this Gene ID
UniProt
View information about CD69 on UniProt.org

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