PE anti-human/mouse integrin β7 Antibody
- 产品名称：
- PE anti-human/mouse integrin β7 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 121005
- 产品应用：
- 121005
- Verified Reactivity
- Mouse, Human
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- TK1 cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application References
(PubMed link indicates BioLegend citation) -
- Andrew DP, et al. 1994. J. Immunol. 153:3847. (Block)
- Berlin C, et al. 1993. Cell 74:185. (Block)
- Tidswell M, et al. 1997. J. Immunol. 159:1497. (Block)
- Product Citations
-
- Brice?o O, et al. 2016. PLoS One. 11:e0166496. PubMed
- Port JR, et al. 2020. J Virol. 94:. PubMed
- Samarani S, et al. 2020. Mediators Inflamm. 2020:6401969. PubMed
- Kanemaru K, et al. 2015. PLoS One. 10: 0144436. PubMed
- Sung JA, et al. 2018. Mol Ther. 26:2496. PubMed
- RRID
- AB_1659233 (BioLegend Cat. No. 121005) AB_1659230 (BioLegend Cat. No. 121006)
- Structure
- Integrin family, Ig superfamily, 130 kD, heterodimer with CD49d or CD103
- Distribution
-
CD49d/?7: majority of lymphocytes, thymocyte subset, and some bone marrow progenitors; CD103/?7: intestinal intraepithelial lymphocytes (IEL), dendritic epidermal T cells, subset of CD8 T cells in lymph nodes
- Function
- Lymphocyte adhesion, hematopoietic progenitor cells migration
- Ligand/Receptor
- CD49d/?7: VCAM-1 (CD106), MAdCAM-1 and fibronectin; CD103/?7: E-cadherin
- Cell Type
- Hematopoietic stem and progenitors, Lymphocytes, T cells, Thymocytes, Tregs
- Biology Area
- Cell Biology, Immunology, Neuroscience, Synaptic Biology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Andrew DP, et al. 1994. J. Immunol. 153:3847.
2. Picarella D, et al. 1997. J. Immunol. 158:2099.
3. Lefrancois L, et al. 1994. Eur. J. Immunol. 24:635
4. Cepek KL, et al. 1994. Nature 372:190.
- Gene ID
- 16421 View all products for this Gene ID 3695 View all products for this Gene ID
- UniProt
- View information about Integrin beta7 on UniProt.org
