Purified anti-hnRNPK Antibody
- 产品名称：
- Purified anti-hnRNPK Antibody
- 产品类别：
- 抗体
- 产品编号：
- 634601
- 产品应用：
- 634601
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Ovalbumin-conjugated synthetic Peptide SVKQYSGKFF
- Formulation
- This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide at 0.5 mg/ml.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 5 ?g antibody per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.
- Application References
(PubMed link indicates BioLegend citation) -
- Carpenter B, et al. 2006. Br J Cancer. 95:921. PubMed
- Carpenter B, et al. 2007. Br J Cancer. 97:574. PubMed
- Alnabulsi A, et al. 2009. Methods of cancer diagnosis, therapy and diagnosis. 4:25.
- Product Citations
-
- Carpenter B, et al. 2006. Br J Cancer. 95:921. PubMed
- Roychoudhury P, Chaudhuri K 2007. Br J Cancer. 97:574. PubMed
- RRID
- AB_2120365 (BioLegend Cat. No. 634601) AB_2120361 (BioLegend Cat. No. 634602)
- Structure
- Heterogenous nuclear ribonucleoprotein family, KH domains; 51 kD
- Distribution
-
Ubiquitously expressed cytoplasmic and nuclear protein
- Function
- Pre-mRNA binding protein, component of hnRNP complexes providing substrate for pre-mRNA processing before becoming translatable mRNAs in cytoplasm. Acts as transcriptional regulator and functions in nucleocytoplasmic shuttling
- Interaction
- Interacts with Csk, NCK2, Vav1, ITK, CEBP β, c-Src, Fyn, Lyn, Hepatitis virus core protein
- Modification
- Phosphorylation (PKC δ, c-Src), Acetylation, Methylation
- Biology Area
- Cell Biology, Transcription Factors
- Molecular Family
- Nuclear Markers
- Antigen References
-
1. Matunis MJ, et al. 1992. Mol. Cell. Biol. 12:164.
2. Dejgaard K, et al. 1994. J. Mol. Biol. 236:33.
3. Mandal M, et al. 2001. J. Biol. Chem. 276:9699
- Regulation
- Epidermal growth factor (EGF) can increase expression and function
- Gene ID
- 3190 View all products for this Gene ID
- UniProt
- View information about hnRNPK on UniProt.org
