Purified anti-ATIC Antibody
- 产品名称：
- Purified anti-ATIC Antibody
- 产品类别：
- 抗体
- 产品编号：
- 635602
- 产品应用：
- 635602
- Verified Reactivity
- Human, Mouse, Rat, Frog, and Fruit fly
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Ovalbumin-conjugated synthetic Peptide AHTNLRLFHH
- Formulation
- This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide at 0.5 mg/ml.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- Upon receipt, store undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
KO/KD-WB - Verified
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, suggested working dilution(s): Use 5-10 ?g per 5 ml antibody dilution buffer for each mini-gel.? It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2227799 (BioLegend Cat. No. 635602)
- Structure
- Belongs to the purH family, the IMP cyclohydrolase activity resides in the N-terminal region. Predicted molecular weight approximately 65 kD.
- Distribution
-
Cytoplasm
- Function
- ATIC catalyzes the penultimate and final steps in the de novo purine biosynthesis pathway. ATIC acts as a bifunctional enzyme catalyze the formation of FAICAR and IMP.
- Interaction
- CDK2, Stomatin, JAK1, NM23B, IKKE, HNRNP, CIA30
- Biology Area
- Cell Biology
- Antigen References
-
1. Rayl EA, et al. 1996. J. Biol. Chem. 271:2225
- Gene ID
- 471 View all products for this Gene ID
- UniProt
- View information about ATIC on UniProt.org
