Purified anti-MMP3 Antibody
- 产品名称：
- Purified anti-MMP3 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 634902
- 产品应用：
- 634902
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Ovalbumin-conjugated synthetic peptide CKSLRKLEPELH
- Formulation
- This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide at 0.5 mg/ml.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- Upon receipt, store undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
IHC-P, ELISA - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, suggested working dilution(s): Use 4 ?g/ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.
- Application References
(PubMed link indicates BioLegend citation) -
- Murray G et al. 1998. Gut. 43:791.
- Cheng Z, et al. 2011. Eur J Pharmacol. 664:20. PubMed.
- Product Citations
-
- Cheng Z, et al. 2011. Eur J Pharmacol. 664:20. PubMed
- RRID
- AB_2146594 (BioLegend Cat. No. 634902)
- Structure
- Belongs to the peptidase M10A family. Contains 4 hemopexin-like domains, predicted molecular weight approximately 54 kD.
- Distribution
-
Extracellular
- Function
- MMP3 degrades fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase. MMP-3 is thought to play a prominent role in the pathogenesis of rheumatoid arthritis.
- Interaction
- MCP1-4, TIMP1, TIMP3, Decorin, Testican 3, Plasminogen, Aggrecan 1, Osteopontin, IBP-3
- Biology Area
- Angiogenesis, Cell Adhesion, Cell Biology, Neuroinflammation, Neuroscience
- Molecular Family
- Enzymes and Regulators
- Antigen References
-
1. Saus J, et al. 1988. J. Biol. Chem. 263:6742
- Gene ID
- 4314 View all products for this Gene ID
- UniProt
- View information about MMP-3 on UniProt.org
