Purified anti-MMP1 Antibody
- 产品名称：
- Purified anti-MMP1 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 634702
- 产品应用：
- 634702
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Ovalbumin-conjugated synthetic peptide CSSFGFPRTVKH
- Formulation
- This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide at 0.5 mg/ml.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
IHC-P - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 4 ?g/ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.
- Application References
(PubMed link indicates BioLegend citation) -
- Murray G et al. 1998. Gut. 43:791.
- Murray G et al. 1998. J. Pathol. 185:256.
- RRID
- AB_2144281 (BioLegend Cat. No. 634702)
- Structure
- Belongs to the peptidase M10A family. Contains 4 hemopexin-like domains, predicted molecular weight approximately 54 kD.
- Distribution
-
Extracellular
- Function
- MMP1 cleaves collagens of types I, II, III, VII and X. MMP-1 is thought to play an important role in rheumatoid and osteo-arthritis pathogenesis as mediators of cartilage and bone destruction.
- Interaction
- MCP1, MCP3, MCP4, TIMP-1, MMP7, Collagen type II α1, IBP-3, Integrin α2, CD44, CD147, Brevican, Chymase 1, Aggrecan 1
- Biology Area
- Angiogenesis, Cell Adhesion, Cell Biology, Neuroinflammation, Neuroscience
- Molecular Family
- Enzymes and Regulators
- Antigen References
-
1. Boire A, et al. 2005. Cell 120:303
- Gene ID
- 4312 View all products for this Gene ID
- UniProt
- View information about MMP-1 on UniProt.org
