Purified anti-human CD23 Antibody
- 产品名称：
- Purified anti-human CD23 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 338502
- 产品应用：
- 338502
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
IP - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application References
(PubMed link indicates BioLegend citation) -
- Sugden B and Metzenberg S. 1983. J. Virol. 46:800-807.
- Product Citations
-
- Heesters BA, et al. 2021. J Exp Med. 218:. PubMed
- Eccles JD, et al. 2020. Cell Rep. 30:351. PubMed
- Chevrier S, et al. 2018. Cell Syst. 0.675. PubMed
- RRID
- AB_1279181 (BioLegend Cat. No. 338502)
- Structure
- Ig family member, type II transmembrane glycoprotein, 45 kD
- Distribution
-
B cells, follicular dendritic cells, monocytes, eosinophils, a subset of T cells, Langerhans cells
- Function
- Regulation of IgE synthesis in human monocytes; CD23 triggering results in release of pro-inflammatory cytokines including TNF-a, IL-1, IL-6, and GM-CSF
- Ligand/Receptor
- IgE, CD19/CD21/CD81
- Cell Type
- B cells, Dendritic cells, Eosinophils, Langerhans cells, Monocytes, T cells
- Biology Area
- Immunology
- Molecular Family
- CD Molecules, Fc Receptors
- Antigen References
-
1. Ludin C, et al. 1987. EMBO J. 6:109.
2. Delespesse G, et al. 1992. Immunol. Rev. 125:77.
3. Flores-Romo L, et al. 1993. Science 261:1038.
4. Armant M, et al. 1994. J. Exp. Med. 180:1005.
- Gene ID
- 2208 View all products for this Gene ID
- UniProt
- View information about CD23 on UniProt.org
