PE anti-mouse RAE-1γ Antibody -上海雅吉生物科技有限公司

规格	价格	库存
50µg	￥ 1464	1

Product Details

Verified Reactivity

Mouse

Antibody Type

Monoclonal

Host Species

Rat

Immunogen

Mouse RAE-1 gamma transfected cell line

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation

The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.

Concentration

0.2 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 ?g per 10⁶ cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser

Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)

Application References (PubMed link indicates BioLegend citation)

Lodoen M, et al. 2003. J. Exp. Med. 197:1245.

Product Citations

Lis N, et al. 2021. J Cell Sci. 134:. PubMed
Dubrot J, et al. 2021. Immunity. 54(3):571-585.e6. PubMed

RRID

AB_1227755 (BioLegend Cat. No. 130107)

Disclaimer

This product is for in vitro research use only. It is not to be used for commercial purposes. Use of this product to produce products for sale or for diagnostic therapeutic or drug discovery purposes is prohibited. In order to obtain a license to use this product for commercial purposes contact The Regents of the University of California.

Antigen Details

Structure: RAE is a family of GPI-anchord surface protein consisting of alpha, beta, gamma, delta and epsilon. They share strong homology within the family and weak homology with MHC class 1 molecule.
Distribution: Expression of RAE-1 is low or absent on normal, adult tissue, but consititutively expressed on some tumors and can be induced by retinoid acid.
Function: As ligands for the mouse activating NKG2D expressed by NK cells
Ligand/Receptor: NKG2D
Biology Area: Immunology
Molecular Family: MHC Antigens
Antigen References: 1. Cerwenka A, et al. 2000. Immnity. 12:721
2. Lodoen M, et al. 2003 J. Exp. Med. 197:1245
3. Diefenbach A, et al. 2001 Nature 413:165
Gene ID: 66679 View all products for this Gene ID
UniProt: View information about RAE-1gamma on UniProt.org

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