Purified anti-human CD318 (CDCP1) Antibody
- 产品名称：
- Purified anti-human CD318 (CDCP1) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 324002
- 产品应用：
- 324002
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- NIH-3T3 cells transfected with human CDCP1
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC -?Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.125 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application References
(PubMed link indicates BioLegend citation) -
- Bühring HJ, et al. 2004. Stem Cells 22:334-343.
- Iwata M, et al. 2014. PLoS One. 9:103904. PubMed
- Product Citations
-
- Iwata M, et al. 2014. PLoS One. 9:109304. PubMed
- RRID
- AB_756052 (BioLegend Cat. No. 324002)
- Structure
- Transmembrane protein containing three CUB domains, predicted molecular weight approximately 93 kD. Alternately spliced isoforms have been reported
- Distribution
-
Marker for immature hematopoietic progenitor cell subsets; also expressed in mesenchymal stem cells and neural progenitor cell populations. Widely distributed in a variety of cell types including keratinocytes, skeletal muscle, colon, kidney, lung, small
- Function
- Unknown, thought to be involved on early hematopoiesis
- Interaction
- Plasminogen, matriptase, c-Src
- Modification
- Phosphorylation (Tyr734) by c-Src; regulated by adhesion or plasmin in epithelial cells
- Cell Type
- Hematopoietic stem and progenitors, Mesenchymal Stem Cells, Neural Stem Cells
- Biology Area
- Cell Biology, Immunology, Neuroscience, Neuroscience Cell Markers, Stem Cells
- Molecular Family
- CD Molecules
- Antigen References
-
1. Brown TA,?et al.?2004.?J. Biol. Chem.?279:14772.
2. Conze T,?et al.?2003.?Ann. N.Y. Acad. Sci.?996:222.
3. Hooper JD,?et al.?2003.?Oncogene?22:1783.
- Gene ID
- 64866 View all products for this Gene ID
- UniProt
- View information about CD318 on UniProt.org
