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APC anti-human CD318 (CDCP1) Antibody
产品名称:
APC anti-human CD318 (CDCP1) Antibody
产品类别:
抗体
产品编号:
324018
产品应用:
324018
[价格]
规格 价格 库存
25tests ¥ 1788 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
NIH-3T3 cells transfected with human CDCP1
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC -?Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser
Red Laser (633 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Bühring HJ, et al. 2004. Stem Cells 22:334-343.
Product Citations
  1. Noskovičová N, et al. 2018. Am J Physiol Lung Cell Mol Physiol. 314:L695. PubMed
RRID
AB_2687091 (BioLegend Cat. No. 324018) AB_2078815 (BioLegend Cat. No. 324008)

Antigen Details

Structure
Transmembrane protein containing three CUB domains, predicted molecular weight approximately 93 kD. Alternately spliced isoforms have been reported
Distribution

Marker for immature hematopoietic progenitor cell subsets; also expressed in mesenchymal stem cells and neural progenitor cell populations. Widely distributed in a variety of cell types including keratinocytes, skeletal muscle, colon, kidney, lung, small

Function
Unknown, thought to be involved on early hematopoiesis
Interaction
Plasminogen, matriptase, c-Src
Modification
Phosphorylation (Y734) by c-Src; regulated by adhesion or plasmin in epithelial cells
Cell Type
Hematopoietic stem and progenitors, Mesenchymal Stem Cells, Neural Stem Cells
Biology Area
Cell Biology, Immunology, Neuroscience, Neuroscience Cell Markers, Stem Cells
Molecular Family
CD Molecules
Antigen References

1. Brown TA,?et al.?2004.?J. Biol. Chem.?279:14772.
2. Conze T,?et al.?2003.?Ann. N.Y. Acad. Sci.?996:222.
3. Hooper JD,?et al.?2003.?Oncogene?22:1783.

Gene ID
64866 View all products for this Gene ID
UniProt
View information about CD318 on UniProt.org

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