Purified anti-Transthyretin, 31-50 Antibody
- 产品名称：
- Purified anti-Transthyretin, 31-50 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 853001
- 产品应用：
- 853001
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant Human Transthyretin
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Qulaity tested
Direct ELISA - Verified
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 1.0 - 5.0 ?g per ml.?For Direct ELISA applications, a concentration range of 0.002 - 0.2 ?g/mL is recommended. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2728603 (BioLegend Cat. No. 853001) AB_2728604 (BioLegend Cat. No. 853002)
- Structure
- TTR is a β-sheet rich homotetrameric protein that has a molecular mass of 55 kD. Each monomer consists of 127 amino acids.
- Distribution
-
Tissue sources: Liver, choroid plexus epithelium, and retina pigment epithelium.
Distribution: Primarily extracellular in blood and cerebrospinal fluid.
- Function
- The normal function of TTR is to transport thyroxine and retinol-binding protein in the blood and cerebrospinal fluid.
- Interaction
- Perlecan, receptor for advanced glycation end product (RAGE)
- Ligand/Receptor
- Thyroxine, retinol-binding protein bound to retinol
- Biology Area
- Cell Biology, Neurodegeneration, Neuroscience, Protein Misfolding and Aggregation
- Molecular Family
- Carrier Proteins
- Antigen References
-
- Plante-Bordeneuve V, et al. 2011. Lancet Neurol. 10:1086. PubMed
- Pinney JH, et al. 2013. J Am Heart Assoc. 2:e000098. PubMed
- Hawkins PN, et al. 2015. Ann Med. 47(8):625. PubMed
- Gene ID
- 7276 View all products for this Gene ID
- UniProt
- View information about Transthyretin 31-50 on UniProt.org
