HRP anti-Transthyretin, 31-50 Antibody
- 产品名称：
- HRP anti-Transthyretin, 31-50 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 853004
- 产品应用：
- 853004
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant Human Transthyretin
- Formulation
- This antibody is provided in 50% glycerol in aqueous buffered solutions with preservatives.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with HRP under optimal conditions.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- Upon receipt, the antibody solution should be stored undiluted at -20°C, and protected from prolonged exposure to light.
- Application
-
WB - Quality tested
IHC-P - Verified
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 5.0 - 10 ?g per ml. For immunohistochemistry, a concentration range of 5.0 - 10 ?g/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2783430 (BioLegend Cat. No. 853004)
- Structure
- TTR is a β-sheet rich homotetrameric protein that has a molecular mass of 55 kD. Each monomer consists of 127 amino acids.
- Distribution
-
Tissue sources: Liver, choroid plexus epithelium, and retina pigment epithelium.
Distribution: Primarily extracellular in blood and cerebrospinal fluid.
- Function
- The normal function of TTR is to transport thyroxine and retinol-binding protein in the blood and cerebrospinal fluid.
- Interaction
- Perlecan, receptor for advanced glycation end product (RAGE)
- Ligand/Receptor
- Thyroxine, retinol-binding protein bound to retinol
- Biology Area
- Cell Biology, Neurodegeneration, Neuroscience, Protein Misfolding and Aggregation
- Molecular Family
- Carrier Proteins
- Antigen References
-
- Plante-Bordeneuve V, et al. 2011. Lancet Neurol. 10:1086. PubMed
- Pinney JH, et al. 2013. J Am Heart Assoc. 2:e000098. PubMed
- Hawkins PN, et al. 2015. Ann Med. 47(8):625. PubMed
- Gene ID
- 7276 View all products for this Gene ID
- UniProt
- View information about Transthyretin 31-50 on UniProt.org
