Purified anti-Rac1 Antibody
- 产品名称：
- Purified anti-Rac1 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 854101
- 产品应用：
- 854101
- Verified Reactivity
- Mouse, Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant full-length Rac1 protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
IHC-P - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 5.0 - 10 ?g/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2814570 (BioLegend Cat. No. 854101) AB_2814571 (BioLegend Cat. No. 854102)
- Structure
- Rac1 is a 192 amino acid protein with predicted molecular mass of ~ 21 kD.
- Distribution
-
Tissue Distribution: Ubiquitously expressed
Cellular Distribution: Extracellular, plasma membrane, cytosol, endoplasmic reticulum, and Golgi apparatus
- Function
- Rac1 is activated by GTP binding and deactivated by GTP hydrolysis.
- Interaction
- Rac1 binds to PIP5K1A, RAB7a, SRGAP2, CYFIP1/SRA-1, PLXNB3, and PKN2.
- Biology Area
- Cancer Biomarkers, Cell Motility/Cytoskeleton/Structure, Cell Proliferation and Viability, Cell Structure, Neurodegeneration, Neuroinflammation, Neuroscience
- Molecular Family
- GTPases, Synaptic Vesicle Trafficking/Endocytosis
- Antigen References
-
- Payapilly A, Malliri A. 2018. Curr. Opin. Cell. Biol. 2018.04.009.
- Melzer C, et al. 2017. Cell. Commun. Signal. s12964-017-0175-0.
- Zou T, et al. 2017. Clin. Genet. cge.12908.
- Gene ID
- 19353 View all products for this Gene ID 363875 View all products for this Gene ID
- UniProt
- View information about Rac1 on UniProt.org
