Purified anti-human CD326 (EpCAM) Antibody
- 产品名称：
- Purified anti-human CD326 (EpCAM) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 369802
- 产品应用：
- 369802
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC -?Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application References
(PubMed link indicates BioLegend citation) -
- Strnad J, et al. 1989. Cancer Res. 49:314.
- Munz M, et al. 2004. Oncogene 23:5748.
- Rao CG, et al. 2005. Int. J. Oncol. 27:49.
- RRID
- AB_2686944 (BioLegend Cat. No. 369802)
- Structure
- Type I transmembrane protein, contains six disulfide bridges, one THYRO domain, approximate molecular weight 40 kD.
- Distribution
-
Highly expressed in bone marrow, colon, lung, and most normal epithelial cells. Also highly expressed on carcinomas of gastrointestinal origin. Expressed during early erythrogenesis.
- Function
- Homotypic calcium-independent cell adhesion. CD326 is believed to be involved in carcinogenesis by its ability to induce genes involved in cellular metabolism and proliferation.
- Cell Type
- Epithelial cells
- Biology Area
- Cancer Biomarkers, Cell Biology, Cell Proliferation and Viability, Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1.?Strnad J, et al. 1989. Cancer Res. 49:314.
2. Munz M, et al. 2004. Oncogene 23:5748.
3. Rao CG, et al. 2005. Int. J. Oncol. 27:49.?
- Gene ID
- 4072 View all products for this Gene ID
- UniProt
- View information about CD326 on UniProt.org
